Gene name Source Gene ID Annotation Date Added by
AFF_AC8.J Aff_AC8.J P W
AFF_C25D7.10 Aff_C25D7.10 P W
AFF_C33A11.2 Aff_C33A11.2 P W
AFF_E01A2.I Aff_E01A2.I P W
AFF_F44A2.6 Aff_F44A2.6 P W
AFF_W02A2.E Aff_W02A2.E P W
AFF_Y119D3_465.L Aff_Y119D3_465.L P W
AFF_Y25C1A.A Aff_Y25C1A.A P W
AFF_Y52B11C.1 Aff_Y52B11C.1 P W
AFF_Y53G8A_2706.A Aff_Y53G8A_2706.A P W
AFF_Y59A8A.H Aff_Y59A8A.H P W
AFF_Y71F9A_262.A Aff_Y71F9A_262.A P W
AFF_Y71H2_389.E Aff_Y71H2_389.E P W
B0218.3 Aff_B0218.3 P W All gene names: pmk-1; B0218.3; 4I913; CE06686;
NM_068964; WBGene00004055; WP:CE06686
WormBase description: pmk-1 encodes a mitogen-activated
protein kinase (MAPK), orthologous to human p38 MAPK
(OMIM:600289), that is required for eliciting gonadal
programmed cell death in response to Salmonella
enterica infection; PMK-1 lies upstream of CED-9, a
negative regulator of apoptosis, in the programmed cell
death pathway.
WormBase CDS description: ser/thr kinases
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, wt herm vs wt herm enriched
gen, ViswanathanM et al 2005 S2 sir-2.1 regulated
B0280.10 Aff_B0280.10 P W All gene names: B0280.10; 3I222; CE29533;
WBGene00015105; WP:CE29533
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, list of genes in cluster order, Reinke et al
2004, wt herm vs wt male enriched gen, Reinke et al
2004, list of genes in cluster E, ViswanathanM et al
2005 S2 sir-2.1 regulated
B0507.1 Aff_B0507.1 P W All gene names: B0507.1; 5J259; CE28815;
WBGene00015218; WP:CE28815
Member of lists (Publications lists):
Wang et al 2003 S3 genes pass
one-way ANOVA, Wang et al 2003 S4 LateList, Wang et al
2003 S4 genes pass two-wayANOVA P0
B0507.3 Aff_B0507.3 P W All gene names: B0507.3; 5J251; CE07762; CE39664;
WBGene00015220; WP:CE07762; WP:CE39664
B0547.1 Aff_B0547.1 P W All gene names: csn-5; B0547.1; B0547.1.1; B0547.1.2;
4G415; CE06722; NM_068440; WBGene00000817; WP:CE06722
WormBase description: csn-5 encodes an ortholog of
subunit 5 of the COP9 signalosome complex (CSN5), which
in turn is a pan-eukaryotic multiprotein complex that
positively regulates E3 ubiquitin ligases, physically
interacts with SCF-type E3 ubiquitin ligases, and
probably regulates protein degradation; CSN-5 (along
with KGB-1 and ZYX-1) physically binds germline RNA
helicases (GLH proteins), and csn-5(RNAi) results in
sterile worms with small gonads and no oocytes, causing
oogenesis to cease, but not affecting the initial
assembly of P granules -- a defect essentially
identical to that produced by RNAi with a combination
of glh-1 and glh-4.
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, intrinsic, Reinke et al
2004, wt vs glp-4 enriched genes, ViswanathanM et al
2005 S2 sir-2.1 regulated
B0563.4 Aff_B0563.3 P W All gene names: tag-132; B0563.4; CE30843;
WBGene00006479; WP:CE30843; XJ777
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C01B10.5 Aff_C01B10.5 P W All gene names: hil-7; C01B10.5; C01B10.5b.1;
C01B10.5b.2; H1.Q; 4H411; CE06736; CE26856; CE26857;
CE33357; NM_068626; WBGene00001858; WP:CE06736;
WP:CE26856; WP:CE26857; WP:CE33357
WormBase description: hil-7 encodes a histone H1.1
isoform that is required in the germline for chromatin
silencing (assayed by silencing of transgenic DNA), for
proliferation and differentiation, and for fertility;
hil-7(RNAi) phenotypes resemble the Mes phenotype
resulting from the desilencing of genes required for
somatic differentiation in the germline; HIL-7 is
required in both the hermaphrodite and the male
germlines, and is ubiquitously expressed in all nuclei
(somatic and germline).
C01F4.2 Aff_F57C9.8 P W All gene names: C01F4.2; 1F420; CE30414; CE33358;
WBGene00015303; WP:CE30414; WP:CE33358
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
C01G6.4 Aff_C01G6.4 P W All gene names: C01G6.4; 2J562; CE00866;
WBGene00007226; WP:CE00866
WormBase description: Zinc finger, C3HC4 type (RING
finger)
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C01G8.9 Aff_C01G8.7 P W All gene names: C01G8.9; 1F870; CE30415; CE33359;
WBGene00015314; WP:CE30415; WP:CE33359
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma
C03C10.1 Aff_C03C10.1 P W All gene names: kin-19; C03C10.1; C03C10.1.1;
C03C10.1.2; C03C10.1.3; 3F174; CE00872; NM_065417;
WBGene00002202; WP:CE00872
WormBase description: kin-19 encodes a serine/threonine
kinase orthologous to human casein kinase I, alpha 1
(CSNK1A1, OMIM:600505); KIN-19 appears to be a
component of the non-canonical Wnt signaling pathway
that regulates endoderm formation in the early embryo;
kin-19(RNAi) and mom-2(RNAi) enhance apr-1(RNAi), but
not RNAi of each other.
WormBase CDS description: casein Kinase I
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated
C03H12.1 Aff_ZK662.1 P W All gene names: C03H12.1; CE35380; WBGene00007284;
WP:CE35380; XQ313
C05D9.5 Aff_C05D9.5 P W All gene names: ife-4; C05D9.5; CE07931; NM_075809;
WBGene00002062; WP:CE07931; XB723
WormBase description: The ife-4 gene encodes a member
of the Initiation Factor 4E (eIF4E) family.
WormBase CDS description: initiation factor 4E (EIF-4E)
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
C06A1.1 Aff_C06A1.1 P W All gene names: cdc-48.1; phi-31; C06A1.1; 2K850;
CE02114; NM_063872; WBGene00007352; WP:CE02114
WormBase description: transitional endoplasmic
reticulum ATPase homolog 1 (P97 protein)
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster F,
Reinke et al 2004, list of genes in cluster order,
Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs
glp-4 enriched genes, Reinke et al 2004, GO categories,
ViswanathanM et al 2005 S2 sir-2.1 regulated
C06A6.5 Aff_C06A6.5 P W All gene names: C06A6.5; 4I598; CE27661;
WBGene00015510; WP:CE27661
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster A, Reinke et al 2004, list of genes in cluster
order, ViswanathanM et al 2005 S2 sir-2.1 regulated
C06B8.7 Aff_C06B8.7 P W All gene names: C06B8.7; 5P989; CE30854;
WBGene00007372; WP:CE30854
WormBase description: Human M130 antigen like protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Romagnolo et al 2002 Fig3b
Unkown, ViswanathanM et al 2005 S2 sir-2.1 regulated
C07G1.5 Aff_C07G1.5 P W All gene names: hgrs-1; pqn-9; C07G1.5; 4I966; CE32574;
NM_068974; WBGene00004101; WP:CE32574
WormBase description: The protein product of this gene
is predicted to contain a glutamine/asparagine
(Q/N)-rich ('prion') domain, by the algorithm of
Michelitsch and Weissman (as of the WS77 release of
WormBase, i.e., in wormpep77).
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated
C08B11.7 Aff_C08B11.7 P W All gene names: ubh-4; C08B11.7; 2I328; CE36913;
NM_063283; WBGene00006724; WP:CE36913
WormBase description: thiolesterase
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, intrinsic,
Reinke et al 2004, wt vs glp-4 enriched genes, Reinke
et al 2004, wt herm vs wt male enriched gen, Reinke et
al 2004, GO categories, ViswanathanM et al 2005 S2
sir-2.1 regulated
C09D4.2 Aff_C09D4.2 P W All gene names: C09D4.2; 1G59; CE08031; WBGene00015633;
WP:CE08031
Member of lists (Publications lists):
Baugh et al 2005, validated PAL-1
target genes, Baugh et al 2005, PAL-1 target genes,
Reinke et al 2004, list of genes in cluster A, Reinke
et al 2004, list of genes in cluster order,
ViswanathanM et al 2005 S2 sir-2.1 regulated
C11G6.2 Aff_C11G6.2 P W All gene names: C11G6.2; CE05256; WBGene00007523;
WP:CE05256; XQ943
WormBase description: helicase like
C13G3.3 Aff_C13G3.3 P W All gene names: C13G3.3; C13G3.3a.1; C13G3.3a.2;
C13G3.3b.1; C13G3.3b.2; 5L508; CE05279; CE20505;
WBGene00007554; WP:CE05279; WP:CE20505
WormBase description: proteion phosphatase
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, ViswanathanM et
al 2005 S2 sir-2.1 regulated
C13G5.1 Aff_C13G5.1 P W All gene names: ceh-16; C13G5.1; 3J715; CE37477;
NM_066497; WBGene00000439; WP:CE37477
WormBase description: ceh-16 encodes a protein that
contains a homeobox domain.
WormBase CDS description: Engrailed homeotic protein
Member of lists (Publications lists):
Baugh et al 2005, PAL-1 target genes,
McCarroll et al 2004 SFig1-4 conserved w/ Drosoph
C14A11.6 Aff_C14A11.6 P W All gene names: C14A11.6; CE08154; WBGene00015751;
WP:CE08154; XD426
C14B1.3 Aff_C14B1.3 P W All gene names: C14B1.3; 3E793; CE00900;
WBGene00007574; WP:CE00900
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins.
Member of lists (Publications lists):
Reinke et al 2004, mixed sperm soma,
Reinke et al 2004, fem3 enriched genes, Reinke et al
2004, IVb male soma enriched genes, ViswanathanM et al
2005 S2 sir-2.1 regulated
C14B9.8 Aff_C14B9.8 P W All gene names: C14B9.8; 3J230; CE38273;
WBGene00015754; WP:CE38273
WormBase description: C14B9.8 is orthologous to the
human gene PHOSPHORYLASE KINASE, LIVER, ALPHA-2 SUBUNIT
(PHKA2; OMIM:306000), which when mutated leads to liver
glycogenosis.
WormBase CDS description: Phosphorylase kinase
Member of lists (Publications lists):
Jones et al 2001 Dauer specific genes
P<0.05, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke
et al 2004, list of genes in cluster order, Reinke et
al 2004, mixed oogenesis soma, Reinke et al 2004, list
of genes in cluster E, ViswanathanM et al 2005 S2
sir-2.1 regulated, Wang et al 2003 S7 SAGE genes in
the dataset, Wang et al 2003 S8 SAGE genes in the
dauer exit
C14C10.4 Aff_C14C10.4 P W All gene names: C14C10.4; C14C10.4.1; C14C10.4.2; 5N74;
CE05283; WBGene00007587; WP:CE05283
Member of lists (Publications lists):
Reinke et al 2004, wt herm vs wt male
enriched gen, Reinke et al 2004, GO categories, Reinke
et al 2004, herm soma enriched genes, ViswanathanM et
al 2005 S2 sir-2.1 regulated, ViswanathanM et al 2005
S2 daf-16 Resveratrol
C15H9.8 Aff_C15H9.8 P W All gene names: prx-3; C15H9.8; CE04000; NM_076624;
WBGene00004193; WP:CE04000; XG732
WormBase description: prx-3 is orthologous to the human
gene PEROXISOMAL BIOGENESIS FACTOR 3 (PEX3;
OMIM:603164), which when mutated leads to Zellweger
syndrome of complementation group G.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C16C10.5 Aff_C16C10.5 P W All gene names: C16C10.5; 3F260; CE01496;
WBGene00007626; WP:CE01496
WormBase description: Glutaredoxin, Zinc finger, C3HC4
type (RING finger)
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Murphy et al 2003 Fig2 Class2
shorten lifespan
C16D9.6 Aff_C16D9.6 P W All gene names: C16D9.6; 5I726; CE35240;
WBGene00015861; WP:CE35240
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S4 TransientList, Wang et
al 2003 S3 genes pass one-way ANOVA, Wang et al 2003
S4 genes pass two-wayANOVA P0
C18A3.5 Aff_C18A3.5 P W All gene names: C18A3.5; C18A3.5e.1; C18A3.5e.2;
C18A3.5f.1; C18A3.5f.2; C18A3.5f.3; C18A3.5f.4;
C18A3.5f.5; 2G2; CE27708; CE27709; CE27710; CE32130;
CE32131; WBGene00015943; WP:CE27708; WP:CE27709;
WP:CE27710; WP:CE32130; WP:CE32131
WormBase description: RNA binding protein
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, wt herm vs wt male enriched
gen, Reinke et al 2004, mixed oogenesis soma
C18C4.10 Aff_C18C4.10 P W All gene names: klc-2; C18C4.10; C18C4.10b.1;
C18C4.10b.2; C18C4.10b.3; C18C4.10b.4; C18C4.10b.5;
C18C4.10c.1; C18C4.10c.2; C18C4.10d.1; C18C4.10d.2;
5G58; CE27362; CE32802; CE32803; CE36917;
WBGene00002215; WP:CE27362; WP:CE32802; WP:CE32803;
WP:CE36917
WormBase description: klc-2 encodes a kinesin light
chain and was identified as a protein that interacts
with UNC-16 by the yeast two-hybrid system, this
association suggests that KLC-2 may be involved in the
regulation of synaptic vesicle localization by the
UNC-16-JNK signaling complex.
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
C24F3.2 Aff_C24F3.2 P W All gene names: C24F3.2; 4K987; CE18519;
WBGene00007697; WP:CE18519
WormBase description: Dual specificity phosphatase,
catalytic domain
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, intrinsic,
Reinke et al 2004, wt vs glp-4 enriched genes, Reinke
et al 2004, GO categories, ViswanathanM et al 2005 S2
sir-2.1 regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
C24G6.4 Aff_C24G6.4 P W All gene names: Csr-1; nhr-279; nhr-47; C24G6.4;
C24G6.4.1; C24G6.4.2; 5F989; CE27727; NM_072054;
WBGene00003637; WP:CE27727
WormBase description: nhr-47 is predicted to encode a
nuclear hormone receptor (NHR); gene expression of
nhr-47 appears to be induced upon exposure of worm
cultures to estradiol.
WormBase CDS description: zinc finger protein
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
C25G6.2 Aff_C25G6.2 P W All gene names: tsp-9; C25G6.2; CE04083; NM_075831;
WBGene00006635; WP:CE04083; XB865
WormBase description: transpanin
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S4 Early genes, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
C25G6.5 Aff_C25G6.5 P W All gene names: C25G6.5; CE04086; WBGene00016110;
WP:CE04086; XB868
WormBase description: G-protein coupled receptor
(family 1)
Member of lists (Publications lists):
Baugh et al 2005, PAL-1 target genes,
McCarroll et al 2004 SFig1-4 conserved w/ Drosoph
C26E6.6 Aff_C26E6.6 P W All gene names: C26E6.6; C26E6.6.1; C26E6.6.2; 3G25;
CE39477; WBGene00016142; WP:CE39477
WormBase description: This gene encodes a protein
predicted by Eisenberg and coworkers, with 52%
accuracy, to be mitochondrial.
WormBase CDS description: Ribosomal protein L3
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, intrinsic, Reinke et al
2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt
herm vs wt male enriched gen, ViswanathanM et al 2005
S2 sir-2.1 regulated
C27C12.1 Aff_C27C12.1 P W All gene names: C27C12.1; CE05318; WBGene00007771;
WP:CE05318; XP470
Member of lists (Publications lists):
Reinke et al 2004, wt herm vs wt male
enriched gen, ViswanathanM et al 2005 S2 sir-2.1
regulated
C27F2.5 Aff_C27F2.5 P W All gene names: C27F2.5; C27F2.5.1; C27F2.5.2; 3G50;
CE26875; WBGene00016167; WP:CE26875
WormBase description: S. cerevisiae Snf8p
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster A,
Reinke et al 2004, list of genes in cluster order,
ViswanathanM et al 2005 S2 sir-2.1 regulated
C29E4.5 Aff_C29E4.5 P W All gene names: tag-250; C29E4.5; 3J8; CE29682;
CE38589; WBGene00016203; WP:CE29682; WP:CE38589
C30B5.2 Aff_C30B5.2 P W All gene names: C30B5.2; 2G487; CE31889; CE31890;
WBGene00016244; WP:CE31889; WP:CE31890
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C31E10.6 Aff_C31E10.6 P W All gene names: C31E10.6; CE08506; WBGene00007847;
WP:CE08506; XO617
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma,
ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
C32B5.15 Aff_C32B5.15 P W All gene names: C32B5.15; 2B258; CE08523;
WBGene00016308; WP:CE08523
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins.
C32B5.9 Aff_C32B5.9 P W All gene names: C32B5.9; 2B247; CE08517;
WBGene00016302; WP:CE08517
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 daf-16
Resveratrol
C33E10.2 Aff_C33E10.2 P W All gene names: fbxa-120; C33E10.2; CE17491;
WBGene00016346; WP:CE17491; XR913
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; this gene's
encoded protein also contains an FTH/DUF38 motif, which
may also mediate protein-protein interaction.
Member of lists (Publications lists):
Reinke et al 2004, wt herm vs wt male
enriched gen, ViswanathanM et al 2005 S2 sir-2.1
regulated
C33H5.9 Aff_C33H5.9 P W All gene names: C33H5.9; 4I544; CE04152;
WBGene00016376; WP:CE04152
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, wt herm vs wt male enriched
gen, Reinke et al 2004, list of genes in cluster E,
ViswanathanM et al 2005 S2 sir-2.1 regulated
C34E11.1 Aff_C34E11.1 P W All gene names: rsd-3; C34E11.1; C34E11.1.1;
C34E11.1.2; CE03062; NM_077572; WBGene00004682;
WP:CE03062; XM421
WormBase description: yeast hypothetical L8167.6 like
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster A, Reinke et al 2004, list of genes in
cluster order, ViswanathanM et al 2005 S2 sir-2.1
regulated
C34G6.5 Aff_C34G6.5 P W All gene names: C34G6.5; 1G449; CE26909;
WBGene00016421; WP:CE26909
WormBase description: ser/thr-protein kinase
Member of lists (Publications lists):
Jones et al 2001 Non dauer genes
P<0.05, Reinke et al 2004, intrinsic, Reinke et al
2004, wt vs glp-4 enriched genes, Reinke et al 2004,
list of genes in cluster order, Reinke et al 2004, wt
herm vs wt male enriched gen, Reinke et al 2004, list
of genes in cluster E
C34G6.7 Aff_C34G6.7 P W All gene names: pqn-19; C34G6.7; C34G6.7a.1;
C34G6.7a.2; C34G6.7b.1; C34G6.7b.2; 1G480; CE29700;
CE32816; NM_059309; NM_182013; WBGene00004109;
WP:CE29700; WP:CE32816
WormBase description: The protein product of this gene
is predicted to contain a glutamine/asparagine
(Q/N)-rich ('prion') domain, by the algorithm of
Michelitsch and Weissman (as of the WS77 release of
WormBase, i.e., in wormpep77).
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated
C35D10.8 Aff_C35D10.8 P W All gene names: C35D10.8; 3F945; CE29702;
WBGene00016445; WP:CE29702
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, list of genes in cluster order
C35D10.9 Aff_C35D10.9 P W All gene names: ced-4; C35D10.9; 3F943; CE01203;
CE38154; WBGene00000418; WP:CE01203; WP:CE38154
WormBase description: ced-4 encodes a novel protein;
along with CED-3, CED-4 is required for the initiation
of programmed cell death; accordingly, genetic analyses
indicate that ced-3 and ced-4 function upstream of
ced-1, ced-2, and nuc-1 in the programmed cell death
pathway; in yeast two-hybrid experiments, and upon
coexpression in mammalian cells, CED-4 interacts with
CED-9, an anti-apoptotic BCL-2 homolog; coexpression of
CED-4 and CED-9 results in redistribution of CED-4 from
the cytosol to organellar membranes, suggesting that
CED-9 may negatively regulate CED-4 activity by
sequestering CED-4 to intracellular membranes.
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, list of genes in cluster F, Reinke et al
2004, wt vs glp-4 enriched genes, Reinke et al 2004,
list of genes in cluster order, Reinke et al 2004, wt
herm vs wt male enriched gen, ViswanathanM et al 2005
S2 sir-2.1 regulated
C36E8.3 Aff_C36E8.3 P W All gene names: C36E8.3; 3F99; CE30889; WBGene00007982;
WP:CE30889
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
daf-16 Resveratrol
C38C3.5 Aff_F53E2.C P W All gene names: UNC-60A; unc-60; unc-66; C38C3.5;
C38C3.5c.1; C38C3.5c.2; C38C3.5c.3; 5B957; CE20547;
CE20549; CE31893; NM_071026; WBGene00006794;
WP:CE20547; WP:CE20549; WP:CE31893
WormBase description: unc-60 encodes orthologs of actin
depolymerizing factor/cofilin, actin-binding proteins
that regulate actin filament dynamics; one UNC-60
isoform, UNC-60A, primarily binds G-actin,
depolymerizes actin filaments, and inhibits actin
polymerization; UNC-60A is essential during early
embryonic development for polar body extrusion,
cytokinesis, and embryonic patterning; UNC-60B, which
does not inhibit actin polymerization, binds F- and
G-actin and influences the rate of actin polymerization
by the UNC-60B:actin ratio; UNC-60B is required for
actin filament organization in body wall muscle,
locomotion, and for efficient actin filament
disassembly by UNC-78, an actin interactin protein 1
(AIP1) ortholog; UNC-60A and UNC-60B are differentially
expressed: UNC-60A is found in oocytes, embryos, and
the adult gonad and intestine, while UNC-60B is found
in body wall muscle, the vulva, and spermatheca.
Member of lists (Publications lists):
Roy et al 2002 S2 positivecontrol L1
muscle, ViswanathanM et al 2005 S2 sir-2.1 regulated,
Wang et al 2003 S4 Early genes, Wang et al 2003 S3
genes pass one-way ANOVA, Wang et al 2003 S4 genes
pass two-wayANOVA P0
C38D4.6 Aff_C38D4.6 P W All gene names: ceh-3; nob-2; pal-1; C38D4.6;
C38D4.6a.1; C38D4.6a.2; C38D4.6b.1; C38D4.6b.2; 3F896;
CE05383; CE27837; NM_065590; WBGene00003912;
WP:CE05383; WP:CE27837
WormBase description: pal-1 encodes a homeodomain
protein that is the C. elegans Caudal ortholog; PAL-1
is required maternally and embryonically for cell fate
specification and posterior patterning during
embryogenesis; PAL-1 is also required postembryonically
for fate specification of the posterior V6
neuroectoblast during male tail development; PAL-1 is
expressed in posterior blastomeres beginning at the
four-cell stage of embryogenesis and its expression
continues during embryogenesis in posterior-derived
tissues and cells undergoing movement or forming
midline structures; pal-1 is subject to both
transcriptional and translational regulation.
Member of lists (Publications lists):
Baugh et al 2005, validated PAL-1
target genes, Baugh et al 2005, PAL-1 target genes,
Jones et al 2001 Non dauer genes P<0.05, McCarroll et
al 2004 SFig1-4 conserved w/ Drosoph, Reinke et al
2004, fem1 enriched genes, Reinke et al 2004, list of
genes in cluster order, Reinke et al 2004, oogenesis
enriched genes, Reinke et al 2004, wt vs glp-4 enriched
genes, Reinke et al 2004, wt herm vs wt male enriched
gen, Reinke et al 2004, list of genes in cluster E
C39F7.4 Aff_C39F7.4 P W All gene names: rab-1; C39F7.4; C39F7.4.1; C39F7.4.2;
5B742; CE16905; NM_070996; WBGene00004266; WP:CE16905
WormBase description: rab-1 encodes an ortholog of the
small Ras-like GTPase Rab1; by homology, RAB-1 is
predicted to play a role in intracellular vesicle
trafficking, and consistent with this broad role,
large-scale RNAi screens indicate that rab-1 activity
is required for fertility, movement, and survival; in
yeast two-hybrid assays, RAB-1 interacts with TIR-1, a
C. elegans SARM ortholog that is required for innate
immunity; RNAi studies suggest that RAB-1 and TIR-1
likely function in a pathway that controls expression
of antimicrobial peptides such as NLP-29 and NLP-31;
rab-1 also appears to play a role in regulating
polyglutamine protein aggregation, as rab-1(RNAi)
animals show premature accumulation of protein
aggregates; in situ hybridization studies indicate that
rab-1 is broadly expressed, with elevated levels
apparent in the germline.
WormBase CDS description: RAS-related protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated
C44B7.2 Aff_C44B7.2 P W All gene names: C44B7.2; C44B7.2a.1; C44B7.2a.2;
CE25812; CE34752; WBGene00016624; WP:CE25812;
WP:CE34752
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, wt herm vs wt male enriched gen, ViswanathanM et
al 2005 S2 sir-2.1 regulated
C45B2.5 Aff_C45B2.5 P W All gene names: gln-1; C45B2.5; C45B2.5.1; C45B2.5.2;
CE27854; NM_076611; WBGene00001602; WP:CE27854; XG677
WormBase description: Glutamine synthetase
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster C, ViswanathanM et al 2005 S2 sir-2.1
regulated
C46C2.1 Aff_C46C2.1 P W All gene names: wnk-1; C46C2.1; 4J975; CE37331;
CE37332; NM_069202; NM_182275; WBGene00006941;
WP:CE37331; WP:CE37332
WormBase description: wnk-1 is orthologous to the human
gene PROTEIN KINASE, LYSINE-DEFICIENT 1 (PRKWNK1;
OMIM:605232), which when mutated leads to
pseudohypoaldosteronism type II.
WormBase CDS description: serine/threonine kinase
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
C47G2.2 Aff_C47G2.2 P W All gene names: unc-130; C47G2.2; 2L573; CE02166;
NM_064010; WBGene00006853; WP:CE02166
WormBase description: A member of the forkhead domain
family of transcription factors that affects the
generation of the AWA and ASG chemosensory neurons and
is partially required for male tail morphogenesis and
embryogenesis; it is expressed in the AWA and ASG
precursors; it is required for the graded spatial
expression of the UNC-129 TGF-beta guidance factor.
WormBase CDS description: fork head domain protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
C50F2.6 Aff_C50F2.6 P W All gene names: dao-8; fkb-5; C50F2.6; C50F2.6a.1;
C50F2.6a.2; 1E466; CE08912; CE27878; NM_058856;
NM_058857; WBGene00001430; WP:CE08912; WP:CE27878
WormBase description: fkb-5 encodes a homolog of human
FK506 binding protein 9.
Member of lists (Publications lists):
Link et al 2003 T2 Abeta repressed,
Romagnolo et al 2002 Fig3b others, ViswanathanM et al
2005 S2 sir-2.1 regulated, Wang et al 2003 S4
Climbing, Wang et al 2003 S3 genes pass one-way
ANOVA, Wang et al 2003 S4 genes pass two-wayANOVA P0
C52B11.2 Aff_C52B11.2 P W All gene names: tag-303; C52B11.2; CE04258;
WBGene00016871; WP:CE04258; XB927
WormBase description: potassium channel protein
Member of lists (Publications lists):
Jones et al 2001 Dauer specific genes
P<0.05, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Wang et al 2003 S7 SAGE genes in the dataset,
Wang et al 2003 S8 SAGE genes in the dauer exit
C56A3.6 Aff_C56A3.6 P W All gene names: C56A3.6; 5O34; CE32339; WBGene00008345;
WP:CE32339
WormBase description: EF hand (2 domains)
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
D1025.2 Aff_D1025.2 P W All gene names: D1025.2; CE17610; WBGene00008354;
WP:CE17610; XP132
WormBase description: This gene encodes a protein
predicted by Eisenberg and coworkers, with 52%
accuracy, to be mitochondrial.
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Wang et al 2003 S4 Early genes, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
D1044.6 Aff_D1044.6 P W All gene names: D1044.6; 3G626; CE32173;
WBGene00017031; WP:CE32173
Member of lists (Publications lists):
Jones et al 2001 Non dauer genes
P<0.05, Reinke et al 2004, list of genes in cluster F,
Reinke et al 2004, fem1 enriched genes, Reinke et al
2004, wt vs glp-4 enriched genes, Reinke et al 2004,
list of genes in cluster order, Reinke et al 2004,
oogenesis enriched genes, Reinke et al 2004, wt herm vs
wt male enriched gen
D2013.6 Aff_D2013.6 P W All gene names: D2013.6; 2J621; CE00931;
WBGene00008404; WP:CE00931
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
D2023.5 Aff_D2023.5 P W All gene names: D2023.5; 5M306; CE09075;
WBGene00008409; WP:CE09075
WormBase description: thiosulphate sulphurtransferase
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, oogenesis enriched genes,
Reinke et al 2004, wt vs glp-4 enriched genes, Reinke
et al 2004, wt herm vs wt male enriched gen,
ViswanathanM et al 2005 S2 daf-16 Resveratrol,
ViswanathanM et al 2005 S2 sir-2.1 regulated, Wang et
al 2003 S5 genes common to feeding ANOVA, Wang et al
2003 S3 genes pass one-way ANOVA
D2030.5 Aff_D2030.5 P W All gene names: mce-1; D2030.5; 1I159; CE09082;
WBGene00008415; WP:CE09082
WormBase description: B.subtilis YQJC protein like
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
D2045.9 Aff_D2045.9 P W All gene names: D2045.9; CE33988; WBGene00008426;
WP:CE33988
Member of lists (Publications lists):
Romagnolo et al 2002 Fig3b Unkown,
ViswanathanM et al 2005 S2 sir-2.1 regulated, Wang et
al 2003 S4 Early genes, Wang et al 2003 S3 genes
pass one-way ANOVA, Wang et al 2003 S4 genes pass
two-wayANOVA P0
E04A4.1 Aff_E04A4.1 P W All gene names: fbxb-78; E04A4.1; 4F501; CE32346;
WBGene00017116; WP:CE32346
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; its encoded
protein also contains a Pfam-B45 motif of presently
unknown function.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
F01F1.8 Aff_F01F1.8 P W All gene names: cct-6; F01F1.8; F01F1.8a.1; F01F1.8a.2;
F01F1.8b.1; F01F1.8b.2; F01F1.8b.3; 3G944; CE01234;
CE30647; NM_171135; NM_171136; WBGene00000381;
WP:CE01234; WP:CE30647
WormBase description: eukaryotic cytosolic chaperonin;
affects viability and fertility, and is expressed in
various muscle and neuronal cells: near the pharynx,
near the anal sphincter, in the ventral nerve cord and
the nerve ring; occasionally the expression is visible
in hypodermal cells and in some vulval cells.
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, oogenesis enriched genes, ViswanathanM et al 2005
S2 sir-2.1 regulated
F02E9.7 Aff_F02E9.7 P W All gene names: F02E9.7; 1I991; CE09190;
WBGene00008531; WP:CE09190
WormBase description: acid phosphatase
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, list of genes in cluster order, Reinke et al
2004, wt herm vs wt male enriched gen, Reinke et al
2004, GO categories, Reinke et al 2004, list of genes
in cluster E, ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
F08F1.7 Aff_F08F1.7 P W All gene names: tag-123; F08F1.7; CE09254;
WBGene00006472; WP:CE09254; XJ38
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, list of genes in cluster B,
ViswanathanM et al 2005 S2 sir-2.1 regulated
F08G12.3 Aff_F08G12.3 P W All gene names: F08G12.3; CE03168; WBGene00008587;
WP:CE03168; XL921
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma
F09C3.5 Aff_F09C3.3 P W All gene names: fbxb-69; F09C3.5; 1O872; CE24886;
WBGene00008613; WP:CE24886
F09F7.4 Aff_F09F7.4 P W All gene names: F09F7.4; F09F7.4a.1; F09F7.4a.2;
F09F7.4b.1; F09F7.4b.2; F09F7.4b.3; 3G645; CE00689;
CE30654; WBGene00017301; WP:CE00689; WP:CE30654
WormBase description: Enoyl-CoA hydratase
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated,
Wang et al 2003 S4 Early genes, Wang et al 2003 S3
genes pass one-way ANOVA, Wang et al 2003 S4 genes
pass two-wayANOVA P0
F09G2.2 Aff_F09G2.2 P W All gene names: F09G2.2; 5H677; CE37626;
WBGene00017311; WP:CE37626
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
F09G8.3 Aff_F09G8.3 P W All gene names: F09G8.3; 3J357; CE24890;
WBGene00017319; WP:CE24890
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
F10B5.7 Aff_F10B5.7 P W All gene names: rrf-3; F10B5.7; 2I457; CE02178;
NM_063312; WBGene00004510; WP:CE02178
WormBase description: rrf-3 encodes an RNA-directed RNA
polymerase (RdRP) homolog that inhibits somatic RNAi,
and thus promotes activity of repeated genes (e.g.,
multicopy transgenic arrays); the effect of RRF-3 on
RNAi is opposite to that of RRF-1 (which stimulates
somatic RNAi), which might arise from competition by
RRF-3 with RRF-1 or EGO-1 in RNAi formation;
rrf-3(allele) or rrf-3(allele2) mutants are
hypersensitive to somatic RNAi, and conversely suppress
the activity of an integrated rol6 (su1006) transgene.
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, list of genes in cluster F, Reinke et al
2004, wt vs glp-4 enriched genes, Reinke et al 2004,
list of genes in cluster order, Reinke et al 2004, wt
herm vs wt male enriched gen, Romagnolo et al 2002
Fig3b Metabolism
F10C2.5 Aff_F10C2.5 P W All gene names: F10C2.5; CE09309; NM_073617;
WBGene00008646; WP:CE09309
WormBase description: mannosyl-oligosaccharide
alpha-1,2-mannosidase
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, wt herm vs wt male enriched
gen, Reinke et al 2004, mixed oogenesis soma, Reinke et
al 2004, GO categories, Romagnolo et al 2002 Fig3b
Adhesion
F10D7.2 Aff_F10D7.2 P W All gene names: F10D7.2; F10D7.2.1; F10D7.2.2; CE04352;
WBGene00017339; WP:CE04352; XR980
WormBase description: This gene encodes a protein
predicted by Eisenberg and coworkers, with 52%
accuracy, to be mitochondrial.
WormBase CDS description: calcium alpha subunit;
tetracycline resistance
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster B, Romagnolo et al 2002 Fig3b Transporters,
Wang et al 2003 S5 genes common to feeding ANOVA, Wang
et al 2003 S3 genes pass one-way ANOVA
F11A3.2 Aff_F11A3.2 P W All gene names: F11A3.2; 5J997; CE05586; CE38501;
WBGene00008670; WP:CE05586; WP:CE38501
WormBase description: guanine nucleotide exchange
factor
Member of lists (Publications lists):
Lund et al 2002 Fig3C
Germline-intrinsic, McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, mixed oogenesis soma, Reinke
et al 2004, wt herm vs wt male enriched gen, Reinke et
al 2004, GO categories, Reinke et al 2004, list of
genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S3 genes pass one-way
ANOVA, Wang et al 2003 S4 Early genes, Wang et al 2003
S4 genes pass two-wayANOVA P0
F11C1.1 Aff_F11C1.1 P W All gene names: F11C1.1; CE03186; WBGene00008690;
WP:CE03186; XN606
Member of lists (Publications lists):
Jones et al 2001 Dauer specific genes
P<0.05, Romagnolo et al 2002 Fig3b Unkown,
ViswanathanM et al 2005 S2 sir-2.1 regulated, Wang et
al 2003 S6 removed genes of contamination, Wang et al
2003 S7 SAGE genes in the dataset, Wang et al 2003 S8
SAGE genes in the dauer exit
F11E6.1 Aff_F11E6.1 P W All gene names: F11E6.1; 4S421; CE20669; CE26698;
CE31166; WBGene00008706; WP:CE20669; WP:CE26698;
WP:CE31166
WormBase description: F11E6.1 is homologous to to the
human gene GLUCOCEREBROSIDASE (GBA; OMIM:606463), which
when mutated leads to Gaucher disease.
Member of lists (Publications lists):
Reinke et al 2004, wt herm vs wt herm
enriched gen, Reinke et al 2004, fem3 enriched genes,
Reinke et al 2004, IVb male soma enriched genes, Reinke
et al 2004, mixed sperm soma, ViswanathanM et al 2005
S2 sir-2.1 regulated, Wang et al 2003 S3 genes pass
one-way ANOVA, Wang et al 2003 S4 Climbing, Wang et al
2003 S4 genes pass two-wayANOVA P0
F11G11.7 Aff_F11G11.7 P W All gene names: dnj-9; F11G11.7; 2F149; CE07060;
NM_062471; WBGene00001027; WP:CE07060
WormBase description: This gene encodes a protein
containing a DnaJ ('J') domain.
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, wt herm vs wt
male enriched gen, Reinke et al 2004, herm soma
enriched genes, ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S4 Early genes, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
F12F6.6 Aff_F12F6.6 P W All gene names: sec-24.1; F12F6.6; 4M328; CE05594;
NM_069777; WBGene00004755; WP:CE05594
WormBase description: sec-24.1 encodes one of two C.
elegans Sec24 homologs; in Saccharomyces cerevisiae,
Sec24 is a member of the Sec24-Sec23 subunit of the
COPII coat complex, assembly of which is essential for
the first step of secretory protein transport from the
endoplasmic reticulum (ER) to the Golgi; by homology
with Sec24, SEC-24.1 is predicted to facilitate vesicle
cargo selection, and likely contains multiple,
independent sites for binding to secreted proteins;
loss of sec-24.1 activity via RNAi indicates that
SEC-24.1 is required for cuticle secretion and
oogenesis.
WormBase CDS description: Yeast hypothetical YIK9
protein like
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
F13D12.4 Aff_F13D12.4 P W All gene names: alh-8; F13D12.4; F13D12.4a.1;
F13D12.4a.2; F13D12.4a.3; F13D12.4a.4; 2M21; CE02183;
CE36262; WBGene00000114; WP:CE02183; WP:CE36262
WormBase description: alh-8 is orthologous to the human
gene METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE
(ALDH6A1; OMIM:603178), which when mutated leads to
MMSDH deficiency.
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
F13G3.11 Aff_F13G3.7 P W All gene names: F13G3.11; F13G3.11.1; F13G3.11.2;
1H885; CE28913; WBGene00008769; WP:CE28913
F13H10.4 Aff_F13H10.4 P W All gene names: F13H10.4; 4L782; CE05625;
WBGene00008775; WP:CE05625
WormBase description: F13H10.4 is orthologous to the
human gene A-GLUCOSIDASE I (GCS1; OMIM:601336), which
when mutated leads to disease.
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster F,
Reinke et al 2004, list of genes in cluster order,
Reinke et al 2004, wt herm vs wt male enriched gen,
ViswanathanM et al 2005 S2 sir-2.1 regulated, Wang et
al 2003 S5 genes common to feeding ANOVA, Wang et al
2003 S3 genes pass one-way ANOVA
F14F3.2 Aff_F14F3.2 P W All gene names: F14F3.2; CE31478; WBGene00008805;
WP:CE31478; XL145
WormBase description: ankyrin motif
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated, Wang et al 2003 S4 Early genes,
Wang et al 2003 S3 genes pass one-way ANOVA, Wang et
al 2003 S4 genes pass two-wayANOVA P0
F18C5.10 Aff_F18C5.4 P W All gene names: F18C5.10; F18C5.10.1; F18C5.10.2;
2G850; CE31790; WBGene00017563; WP:CE31790
F19H8.1 Aff_F19H8.1 P W All gene names: tps-2; F19H8.1; CE37507; NM_064634;
WBGene00006603; WP:CE37507
WormBase description: tps-2 encodes one of two
trehalose-6-phosphate synthase proteins in C. elegans,
and RNAi of both enzymes leads to a more than 90%
reduction decrease in trehalose levels, but does not
appear to affect viability or development; the tps-2
mRNA is expressed throughout development.
WormBase CDS description: trehalose phosphate synthase
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Murphy et al 2003 Fig2 Class1 elongate
lifespan
F20B6.2 Aff_F20B6.2 P W All gene names: vha-12; F20B6.2; F20B6.2.1; F20B6.2.2;
CE04424; NM_076310; WBGene00006921; WP:CE04424; XE811
WormBase description: vacuolar ATP synthase (strong)
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, list of genes in cluster C,
ViswanathanM et al 2005 S2 sir-2.1 regulated, Wang et
al 2003 S4 Early genes, Wang et al 2003 S3 genes
pass one-way ANOVA, Wang et al 2003 S4 genes pass
two-wayANOVA P0
F20D1.3 Aff_F20D1.3 P W All gene names: F20D1.3; F20D1.3.1; F20D1.3.2; CE31486;
WBGene00008975; WP:CE31486; XP595
F21G4.2 Aff_F21G4.2 P W All gene names: mrp-4; F21G4.2; CE09548; NM_077257;
WBGene00003410; WP:CE09548; XK507
WormBase description: The mrp-4 gene encodes a homolog
of human CFTR, which when mutated leads to cystic
fibrosis (OMIM:219700).
WormBase CDS description: multidrug
resistance-associated protein
Member of lists (Publications lists):
Lund et al 2002 Fig3D Oocyte-en,
Reinke et al 2004, list of genes in cluster F, Reinke
et al 2004, fem1 enriched genes, Reinke et al 2004,
list of genes in cluster order, Reinke et al 2004,
oogenesis enriched genes, Reinke et al 2004, wt vs
glp-4 enriched genes, Reinke et al 2004, wt herm vs wt
male enriched gen, Reinke et al 2004, GO categories,
ViswanathanM et al 2005 S2 sir-2.1 regulated
F23F1.3 Aff_F23F1.3 P W All gene names: F23F1.3; 2A323; CE31795;
WBGene00017744; WP:CE31795
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
F25B4.8 Aff_F25B4.8 P W All gene names: F25B4.8; 5G170; CE30761; CE30762;
WBGene00017771; WP:CE30761; WP:CE30762
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
F25H5.6 Aff_F25H5.6 P W All gene names: F25H5.6; F25H5.6.1; F25H5.6.2; 1J734;
CE29591; WBGene00009128; WP:CE29591
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, wt vs glp-4 enriched genes,
Reinke et al 2004, oogenesis enriched genes,
ViswanathanM et al 2005 S2 sir-2.1 regulated
F26B1.2 Aff_F26B1.2 P W All gene names: F26B1.2; F26B1.2c.1; F26B1.2c.2;
F26B1.2c.3; 1G895; CE09674; CE33057; CE33058; CE33059;
CE33060; WBGene00017816; WP:CE09674; WP:CE33057;
WP:CE33058; WP:CE33059; WP:CE33060
WormBase description: RNA-binding protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, wt vs glp-4 enriched genes,
Reinke et al 2004, oogenesis enriched genes,
ViswanathanM et al 2005 S2 sir-2.1 regulated, Wang et
al 2003 S5 genes common to feeding ANOVA, Wang et al
2003 S3 genes pass one-way ANOVA
F26D11.11 Aff_F26D11.11 P W All gene names: let-413; F26D11.11; 5I454; CE29778;
CE37008; NM_072650; WBGene00002632; WP:CE29778;
WP:CE37008
WormBase description: let-413 encodes a protein with
strong similarity to human ERBIN, rat DENSIN,
Drosophila SCRIB and its human ortholog hSCRIB; LET-413
protein is localized to the basolateral region of
epithelial cells, and is required for the assembly of
adherens junctions.
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
F27D4.2 Aff_F27D4.2 P W All gene names: F27D4.2; F27D4.2.1; F27D4.2.2;
F27D4.2.3; F27D4.2.4; 1I282; CE36140; WBGene00009188;
WP:CE36140
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, list of genes in cluster order, Reinke et al
2004, wt herm vs wt male enriched gen, Reinke et al
2004, list of genes in cluster E, ViswanathanM et al
2005 S2 sir-2.1 regulated
F27D4.5 Aff_F27D4.5 P W All gene names: tag-173; F27D4.5; F27D4.5.1; F27D4.5.2;
1I305; CE05736; WBGene00006518; WP:CE05736
WormBase description: tag-173/F27D4.5 is orthologous to
the human gene BRANCHED CHAIN KETO ACID DEHYDROGENASE
E1, ALPHA POLYPEPTIDE (BCKDHB; OMIM:248600), which when
mutated leads to maple syrup urine disease, type 1a;
F27D4.5 protein is predicted to be mitochondrial.
WormBase CDS description: 2-oxoisovalerate
dehydrogenase
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster order, Reinke et al 2004, list of genes in
cluster C, ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S4 Climbing, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
F27E5.2 Aff_F27E5.2 P W All gene names: pax-3; F27E5.2; 2K439; CE35862;
NM_063788; WBGene00003939; WP:CE35862
WormBase description: pax-3 encodes a divergent
paired-like homeodomain protein that does not belong to
the Q50, K50, or S50 classes; PAX-3 is required for
locomotion and vulval development; pax-3(RNAi) animals
have consistent Pvl and Unc phenotypes (as well as less
consistent Bmd, Rup, and Stp phenotypes).
WormBase CDS description: 'Paired box' domain, homeobox
protein (paired subfamily)
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
F28B3.1 Aff_F28B3.1 P W All gene names: F28B3.1; 1F517; CE36644;
WBGene00017882; WP:CE36644
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke
et al 2004, mixed oogenesis soma, Reinke et al 2004, GO
categories, ViswanathanM et al 2005 S2 sir-2.1
regulated
F28D1.10 Aff_F28D1.10 P W All gene names: gex-3; F28D1.10; 4N171; CE05750;
NM_069967; WBGene00001580; WP:CE05750
WormBase description: The gex-3 gene encodes a homolog
of NAP1/NCKAP1, a mammalian protein ligand of the small
GTPase Rac1, and of Drosophila HEM2/NAP1/KETTE; gex-3
is required for tissue morphogenesis and cell
migrations; in gex-3 mutants, cells differentiate
properly but fail to become organized.
WormBase CDS description: Drosophila dhem transmembrane
protein like
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster F, Reinke et al 2004, fem1 enriched genes,
Reinke et al 2004, list of genes in cluster order,
Reinke et al 2004, wt herm vs wt male enriched gen,
Reinke et al 2004, mixed oogenesis soma, ViswanathanM
et al 2005 S2 sir-2.1 regulated
F29F11.6 Aff_F29F11.6 P W All gene names: CEGLC-7A; Ce-glc-7alpha; glc-7; gsp-1;
F29F11.6; F29F11.6.1; F29F11.6.2; F29F11.6.3;
F29F11.6.4; 5L165; CE20735; NM_073332; WBGene00001747;
WP:CE20735
WormBase description: serine/threonine protein
phosphatase
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
F30A10.10 Aff_F30A10.10 P W All gene names: F30A10.10; 1K87; CE32639;
WBGene00009267; WP:CE32639
WormBase description: ubiquitin carboxyl-termianl
hydrolase
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, list of genes in cluster F, Reinke et al
2004, wt vs glp-4 enriched genes, Reinke et al 2004,
list of genes in cluster order, Reinke et al 2004, wt
herm vs wt male enriched gen, Reinke et al 2004, GO
categories, ViswanathanM et al 2005 S2 sir-2.1
regulated
F30A10.6 Aff_F30A10.6 P W All gene names: F30A10.6; 1K67; CE09807;
WBGene00009264; WP:CE09807
WormBase description: Yeast recessive suppressor RSD1
like
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, list of genes in cluster E,
ViswanathanM et al 2005 S2 sir-2.1 regulated
F32A5.6 Aff_F32A5.6 P W All gene names: prx-13; F32A5.6; 2H540; CE28290;
NM_063112; WBGene00004198; WP:CE28290
WormBase description: prx-13 is orthologous to the
human gene PEX13 (OMIM:601789), which when mutated
leads to Zellweger syndrome or neonatal
adrenoleukodystrophy.
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph
F32B6.1 Aff_F32B6.1 P W All gene names: nhr-4; F32B6.1; F32B6.1.1; F32B6.1.2;
4K645; CE24934; NM_069374; WBGene00003603; WP:CE24934
WormBase description: nhr-4 is predicted to encode a
nuclear hormone receptor (NHR); expression may peak
during the late larval stages, based on mRNA expression
analysis.
WormBase CDS description: Ligand-binding domain of
nuclear hormone receptors, Zinc finger, C4 type (two
domains)
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol, Wang et al 2003 S3 genes pass one-way
ANOVA, Wang et al 2003 S4 Dauer Enriched, Wang et al
2003 S4 genes pass two-wayANOVA P0
F33A8.3 Aff_F33A8.3 P W All gene names: cey-1; F33A8.3; F33A8.3.1; F33A8.3.2;
2L330; CE17755; NM_063965; WBGene00000472; WP:CE17755
WormBase description: cey-1 encodes a protein with a
cold-shock/Y-box domain that is expressed in early
embryonic blastomeres (at the 15-cell stage, i.e.,
pre-gastrulation), but is normally repressed in early
germline blastomeres by PIE-1; it is predicted to be
mitochondrial by phylogenetic profiling.
WormBase CDS description: 'Cold-shock' DNA-binding
domain
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
F33H2.1 Aff_F33H2.1 P W All gene names: dog-1; F33H2.1; 1P610; CE17764;
NM_061217; WBGene00001049; WP:CE17764
WormBase description: dog-1 encodes a predicted DEAH
helicase, orthologous to the human BRCA1-binding
protein BACH1 (OMIM:605882, mutated in early-onset
breast cancer); DOG-1 is required for maintenance of
polyguanine tracts of germline and somatic DNA, and is
proposed to resolve the secondary structure that can
occur in guanine-rich DNA during lagging-strand DNA
synthesis.
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster F, Reinke et al 2004, fem1 enriched genes,
Reinke et al 2004, wt vs glp-4 enriched genes, Reinke
et al 2004, list of genes in cluster order, Reinke et
al 2004, oogenesis enriched genes, ViswanathanM et al
2005 S2 sir-2.1 regulated, ViswanathanM et al 2005 S2
daf-16 Resveratrol
F35D2.3 Aff_F35D2.3 P W All gene names: F35D2.3; 2H861; CE31804;
WBGene00018041; WP:CE31804
Member of lists (Publications lists):
Baugh et al 2005, PAL-1 target genes,
Jones et al 2001 Non dauer genes P<0.05
F35G12.12 Aff_F35G12.12 P W All gene names: F35G12.12; F35G12.12.1; F35G12.12.2;
3F673; CE31499; WBGene00009445; WP:CE31499
Member of lists (Publications lists):
Lund et al 2002 Fig3C
Germline-intrinsic, Lund et al 2002 Fig1
aging-regulated genes, Reinke et al 2004, list of genes
in cluster order, Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, wt herm vs wt male enriched gen, Reinke et al
2004, list of genes in cluster E, ViswanathanM et al
2005 S2 sir-2.1 regulated
F36H2.1 Aff_F36H2.1 P W All gene names: tat-5; F36H2.1; 1J812; CE34183;
CE34184; CE39367; WBGene00009498; WP:CE34183;
WP:CE34184; WP:CE39367
WormBase description: E1-E2 ATPase
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph
F37C12.2 Aff_F37C12.2 P W All gene names: F37C12.2; 3I275; CE00741;
WBGene00018150; WP:CE00741
Member of lists (Publications lists):
Link et al 2003 T2 Abeta induced,
McCarroll et al 2004 SFig1-4 conserved w/ Drosoph,
ViswanathanM et al 2005 S2 sir-2.1 regulated
F37C12.7 Aff_F37C12.7 P W All gene names: F37C12.7; 3I259; CE29312;
WBGene00018152; WP:CE29312
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, intrinsic,
Reinke et al 2004, wt vs glp-4 enriched genes,
ViswanathanM et al 2005 S2 sir-2.1 regulated
F38A5.2 Aff_F38A5.2 P W All gene names: F38A5.2; F38A5.2b.1; F38A5.2b.2;
CE34010; CE34011; WBGene00018161; WP:CE34010;
WP:CE34011
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated, Wang et al 2003 S4 Early genes,
Wang et al 2003 S3 genes pass one-way ANOVA, Wang et
al 2003 S4 genes pass two-wayANOVA P0
F38E9.5 Aff_F38E9.5 P W All gene names: F38E9.5; F38E9.5.1; F38E9.5.2; CE28307;
WBGene00018187; WP:CE28307; XR65
WormBase description: protein tyrosine kinase
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster order, Reinke et al 2004, list of genes in
cluster C
F38H4.9 Aff_F38H4.9 P W All gene names: PP2A-C; let-92; F38H4.9; F38H4.9.1;
F38H4.9.2; 4M623; CE10074; NM_069846; WBGene00002363;
WP:CE10074
WormBase description: let-92 encodes a homolog of
PP2AC, the catalytic subunit of protein phosphatase 2A
(PP2A), identified genetically in screens for essential
genes on chromosome IV; LET-92 may regulate a number of
signal transduction pathways as it is required for
embryogenesis, larval development, Ras-mediated vulval
development, and axonal guidance in the DD and VD
neurons; let-92 interacts genetically with sur-6 which
encodes a regulatory subunit of PP2A; LET-92 protein is
bound both by SMG-2 and by POS-1, and also interacts in
vitro with UNC-51 and UNC-14; LET-92 is expressed
cytoplasmically in nearly all cells and strongly in
many neurons.
WormBase CDS description: serine/threonine protein
phosphatase
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph
F39H11.3 Aff_F39H11.3 P W All gene names: cdk-8; F39H11.3; 1J281; CE32409;
NM_059956; WBGene00000409; WP:CE32409
WormBase description: cdk-8 encodes a member of the
cyclin-dependent serine/threonine protein kinase family
orthologous to human CDK8 (OMIM:603184) which functions
in transcriptional regulation with the positive
regulatory factor cyclin C, is associated with the RNA
polymerase II holoenzyme, and may regulate
gene-specific activators; CDK-8 also contains a
glutamine/asparagine-rich domain; loss of cdk-8
function via RNA-mediated interference (RNAi) results
in sterility in the injected hermaphrodite, suggesting
that in C. elegans, CDK-8 may play a role in germ-line
development.
WormBase CDS description: serine/threonine kinase
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke
et al 2004, list of genes in cluster order, Reinke et
al 2004, mixed oogenesis soma, Reinke et al 2004, wt
herm vs wt male enriched gen, Reinke et al 2004, GO
categories, Reinke et al 2004, list of genes in cluster
E, ViswanathanM et al 2005 S2 sir-2.1 regulated
F40F11.2 Aff_F40F11.2 P W All gene names: F40F11.2; 4M365; CE28557;
WBGene00009587; WP:CE28557
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
F40F9.7 Aff_F40F9.7 P W All gene names: F40F9.7; F40F9.7a.1; F40F9.7a.2;
F40F9.7b.1; F40F9.7b.2; F40F9.7b.3; F40F9.7b.4; 5K213;
CE05856; CE33580; WBGene00009584; WP:CE05856;
WP:CE33580
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
F41E6.6 Aff_F41E6.6 P W All gene names: tag-196; F41E6.6; F41E6.6.1; F41E6.6.2;
5J77; CE35305; WBGene00007055; WBGene00018287;
WP:CE35305
WormBase description: cysteine protease and a protease
inhibitor
Member of lists (Publications lists):
Kwon et al 2004 T1 late-induction
Ethanol-response, Lund et al 2002 Fig1 aging-regulated
genes, Lund et al 2002 Fig4 Mount 15, McCarroll et al
2004 SFig1-4 conserved w/ Drosoph, Reinke et al 2004,
list of genes in cluster A, Reinke et al 2004, list of
genes in cluster order, ViswanathanM et al 2005 S2
daf-16 Resveratrol, ViswanathanM et al 2005 S2 sir-2.1
regulated
F41H10.3 Aff_F41H10.3 P W All gene names: F41H10.3; 4G139; CE10276; CE31694;
WBGene00018316; WP:CE10276; WP:CE31694
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster F, Reinke et al 2004, list of genes in cluster
order, ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
F42G9.4 Aff_F42G9.4 P W All gene names: F42G9.4; 3B379; CE30789;
WBGene00018363; WP:CE30789
Member of lists (Publications lists):
Wang et al 2003 S3 genes pass
one-way ANOVA, Wang et al 2003 S4 Dauer Enriched, Wang
et al 2003 S4 genes pass two-wayANOVA P0
F42H10.7 Aff_F42H10.7 P W All gene names: F42H10.7; 3J578; CE00169; CE37109;
WBGene00018371; WP:CE00169; WP:CE37109
Member of lists (Publications lists):
Lund et al 2002 Fig3C
Germline-intrinsic, McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster F, Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, intrinsic, Reinke et
al 2004, wt vs glp-4 enriched genes, Reinke et al 2004,
wt herm vs wt male enriched gen, ViswanathanM et al
2005 S2 sir-2.1 regulated
F44B9.3 Aff_F44B9.3 P W All gene names: cit-1.2; F44B9.3; 3J103; CE29042;
CE32417; NM_066344; NM_181926; WBGene00000508;
WP:CE29042; WP:CE32417
WormBase description: cit-1.2 encodes one of two C.
elegans cyclin T orthologs; RNAi experiments indicate
that CIT-1.2 functions redundantly with CIT-1.1 to
broadly regulate embryonic transcription; by homology,
CIT-1.1 and CIT-1.2 are predicted to interact with the
CDK-9 kinase to form the P-TEFb transcription
elongation factor that in C. elegans is required for
Ser2, but not Ser5, phosphorylation in the C-terminal
domain (CTD) repeat of AMA-1/PolII.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
F44E2.8 Aff_F44E2.8 P W All gene names: F44E2.8; 3J938; CE32420;
WBGene00018421; WP:CE32420
Member of lists (Publications lists):
Jones et al 2001 Non dauer genes
P<0.05, Reinke et al 2004, fem1 enriched genes, Reinke
et al 2004, Fig2b shared gemlines, Reinke et al 2004,
wt vs glp-4 enriched genes, Reinke et al 2004,
oogenesis enriched genes, Reinke et al 2004, wt males
vs glp4 male enriched , Reinke et al 2004, wt herm vs
wt male enriched gen, ViswanathanM et al 2005 S2
sir-2.1 regulated
F46C5.9 Aff_F46C5.9 P W All gene names: F46C5.9; 2J100; CE10584;
WBGene00009784; WP:CE10584
WormBase description: G-protein
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
F46C8.3 Aff_F46C8.3 P W All gene names: F46C8.3; CE28334; WBGene00018485;
WP:CE28334; XI145
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
F47G4.2 Aff_F47G4.2 P W All gene names: F47G4.2; 1O670; CE19875;
WBGene00009823; WP:CE19875
WormBase description: Leucine Rich Repeat (2 copies)
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, mixed oogenesis soma
F48C1.6 Aff_F48C1.6 P W All gene names: F48C1.6; 1F886; CE10742;
WBGene00018599; WP:CE10742
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S4 Climbing, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
F49D11.9 Aff_F49D11.9 P W All gene names: tag-296; F49D11.9; 1L520; CE17083;
CE33286; WBGene00018632; WP:CE17083; WP:CE33286
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, list of genes in cluster order, Reinke et al
2004, list of genes in cluster E, ViswanathanM et al
2005 S2 sir-2.1 regulated
F52B11.5 Aff_F52B11.5 P W All gene names: F52B11.5; 4O866; CE18725;
WBGene00009927; WP:CE18725
F52D10.2 Aff_F52D10.2 P W All gene names: F52D10.2; CE03388; WBGene00009930;
WP:CE03388; XM208
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
F52D10.3 Aff_F52D10.3 P W All gene names: ftt-2; F52D10.3; F52D10.3a.1;
F52D10.3a.2; F52D10.3b.1; F52D10.3b.2; CE03389;
CE36489; NM_077537; NM_077538; WBGene00001502;
WP:CE03389; WP:CE36489; XM222
WormBase description: 14-3-3 protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, IVb male soma enriched
genes
F52E4.7 Aff_F52E4.7 P W All gene names: F52E4.7; CE10836; WBGene00018703;
WP:CE10836; XD714
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma,
ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
F53B3.5 Aff_F53B3.5 P W All gene names: F53B3.5; CE30142; WBGene00018743;
WP:CE30142; XD492
WormBase description: F53B3.5 encodes a claudin homolog
that may regulate ion channels; F53B3.5 is distantly
similar to mammalian voltage-dependent calcium channel
gamma subunits that are known or suspected to prevent
epilepsy in vivo (e.g., stargazin; MGI:1316660);
F53B3.5 has no obvious function in mass RNAi assays;
claudins are integral membrane proteins with four
transmembrane sequences that are found in mammalian
tight junctions (TJs), induce TJs when transgenically
expressed in cells normally lacking them, and can
mediate the specific conductance of of specific ions
(e.g., magnesium or calcium) through TJs while blocking
the flow of water.
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster A, Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, wt herm vs wt male
enriched gen, Wang et al 2003 S4 Climbing, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
F54B11.3 Aff_F54B11.3 P W All gene names: unc-84; F54B11.3; CE27761; CE28236;
WBGene00006816; WP:CE27761; WP:CE28236; XO207
WormBase description: unc-84 encodes a transmembrane
protein that contains a SUN domain with homology to S.
pombe Sad1 and affects nuclear migration and anchoring
of various cell types together with UNC-83 and ANC-1,
thereby affecting coordinated locomotion, vulval
formation, and egg laying; UNC-84 is localized to the
nuclear envelope and requires LMN-1 for this
localization, and it is expressed in the nuclear
envelope of essentially all adult and embryonic cells.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
F54D11.2 Aff_F54D11.2 P W All gene names: F54D11.2; F54D11.2.1; F54D11.2.2;
F54D11.2.3; 5F105; CE30805; WBGene00018812; WP:CE30805
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, wt vs glp-4 enriched genes,
Reinke et al 2004, oogenesis enriched genes,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
F54D5.8 Aff_F54D5.8 P W All gene names: dnj-13; F54D5.8; 2L839; CE03412;
NM_064067; WBGene00001031; WP:CE03412
WormBase description: This gene encodes a protein
containing a DnaJ ('J') domain.
WormBase CDS description: DNAJ protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, wt herm vs wt male enriched
gen, ViswanathanM et al 2005 S2 sir-2.1 regulated
F54F3.4 Aff_F54F3.4 P W All gene names: F54F3.4; 5N403; CE19894;
WBGene00010063; WP:CE19894
WormBase description: This gene encodes a protein
predicted by Eisenberg and coworkers, with 68%
accuracy, to be mitochondrial.
WormBase CDS description: dehydrogenase
Member of lists (Publications lists):
Wang et al 2003 S6 removed genes of
contamination
F54H12.3 Aff_F54H12.3 P W All gene names: F54H12.3; 3J48; CE00545;
WBGene00018843; WP:CE00545
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
F55A12.2 Aff_F55A12.2 P W All gene names: F55A12.2; F55A12.2d.1; F55A12.2d.2;
1F933; CE29396; CE30540; CE34317; CE34318;
WBGene00018863; WP:CE29396; WP:CE30540; WP:CE34317;
WP:CE34318
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
F55F8.3 Aff_F55F8.3 P W All gene names: F55F8.3; 1G218; CE30542;
WBGene00018891; WP:CE30542
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, intrinsic, Reinke et al
2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt
herm vs wt male enriched gen, ViswanathanM et al 2005
S2 sir-2.1 regulated, Wang et al 2003 S5 genes common
to feeding ANOVA, Wang et al 2003 S3 genes pass
one-way ANOVA
F55H2.2 Aff_F55H2.2 P W All gene names: vha-14; F55H2.2; F55H2.2.1; F55H2.2.2;
3K599; CE00209; NM_066693; WBGene00010130; WP:CE00209
WormBase description: Membrane-associated atpase gamma
chain
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated,
Wang et al 2003 S4 Climbing, Wang et al 2003 S3
genes pass one-way ANOVA, Wang et al 2003 S4 genes
pass two-wayANOVA P0
F56D2.2 Aff_F56D2.2 P W All gene names: F56D2.2; 3G677; CE11228;
WBGene00018964; WP:CE11228
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, list of genes in cluster order, Reinke et al
2004, wt herm vs wt male enriched gen, Reinke et al
2004, list of genes in cluster E, ViswanathanM et al
2005 S2 sir-2.1 regulated, ViswanathanM et al 2005 S2
daf-16 Resveratrol
F56H9.5 Aff_F56H9.5 P W All gene names: lin-25; F56H9.5; 5N137; CE05975;
NM_073761; WBGene00003011; WP:CE05975
WormBase description: lin-25
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, wt herm vs wt male enriched
gen, Reinke et al 2004, mixed oogenesis soma,
ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
F57B9.2 Aff_F57B9.2 P W All gene names: ntl-1; F57B9.2; 3I47; CE01337;
NM_066115; WBGene00003824; WP:CE01337
Member of lists (Publications lists):
Lund et al 2002 Fig1 aging-regulated
genes, McCarroll et al 2004 SFig5 conserved w/ yeast,
McCarroll et al 2004 SFig1-4 conserved w/ Drosoph,
Reinke et al 2004, list of genes in cluster F, Reinke
et al 2004, fem1 enriched genes, Reinke et al 2004,
list of genes in cluster order, Reinke et al 2004,
mixed oogenesis soma, Reinke et al 2004, GO categories,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
F57B9.7 Aff_T07E3.7 P W All gene names: F57B9.7; 3I14; CE31011; CE31012;
WBGene00018998; WP:CE31011; WP:CE31012
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, wt vs glp-4 enriched genes,
Reinke et al 2004, oogenesis enriched genes, Reinke et
al 2004, wt herm vs wt male enriched gen, Reinke et al
2004, mixed oogenesis soma, ViswanathanM et al 2005 S2
sir-2.1 regulated
F57G12.1 Aff_F57G12.1 P W All gene names: F57G12.1; F57G12.1.1; F57G12.1.2;
CE03426; WBGene00010221; WP:CE03426; XM788
Member of lists (Publications lists):
Lund et al 2002 Fig1 aging-regulated
genes, ViswanathanM et al 2005 S2 sir-2.1 regulated
F58F9.7 Aff_F58F9.7 P W All gene names: F58F9.7; F58F9.7.1; F58F9.7.2; 4H10;
CE07304; WBGene00019060; WP:CE07304
WormBase description: acyl-coenzyme A oxidase
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster order, Reinke et al 2004, list of genes in
cluster C, ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S3 genes pass one-way
ANOVA, Wang et al 2003 S4 Dauer Enriched, Wang et al
2003 S4 genes pass two-wayANOVA P0
F58G11.2 Aff_F58G11.2 P W All gene names: F58G11.2; 5O149; CE11402;
WBGene00010280; WP:CE11402
WormBase description: ATP-dependent RNA helicase like
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
F58G11.6 Aff_F58G11.6 P W All gene names: F58G11.6; 5O161; CE11410;
WBGene00010283; WP:CE11410
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, wt vs glp-4 enriched genes,
Reinke et al 2004, oogenesis enriched genes, Reinke et
al 2004, wt herm vs wt male enriched gen
F58H1.1 Aff_F58H1.1 P W All gene names: F58H1.1; 5M408; CE06025; CE39509;
WBGene00010284; WP:CE06025; WP:CE39509
WormBase description: alpha-mannosidase
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
F58H7.7 Aff_F58H7.7 P W All gene names: F58H7.7; 4B667; CE34326;
WBGene00019072; WP:CE34326
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins.
H12C20.2 Aff_F38B7.7 P W All gene names: pms-2; H12C20.2; 5M48; CE18807;
CE19915; NM_073532; NM_073533; WBGene00004064;
WP:CE18807; WP:CE19915
WormBase description: DNA mismatch repair protein
(PMS2)
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, wt herm vs wt male enriched gen
H20J04.6 Aff_H20J04_717.A P W All gene names: H20J04.6; H20J04.B; 2E613; CE20973;
WBGene00019221; WP:CE20973
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
K01A6.2 Aff_K01A6.1 P W All gene names: magi-1; K01A6.2; 4M493; CE37387;
WBGene00010444; WP:CE37387
WormBase description: membrane-associated guanylate
kinase homolog (MAGUK)
Member of lists (Publications lists):
Murphy et al 2003 Fig2 Class1
elongate lifespan, ViswanathanM et al 2005 S2 daf-16
Resveratrol
K01G5.1 Aff_K01G5.1 P W All gene names: tag-331; K01G5.1; 3K846; 3L846;
CE26718; WBGene00010476; WP:CE26718
WormBase description: Zinc finger, C3HC4 type (RING
finger)
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, intrinsic, Reinke et al
2004, wt vs glp-4 enriched genes, Reinke et al 2004,
list of genes in cluster order, Reinke et al 2004, wt
herm vs wt male enriched gen, Reinke et al 2004, list
of genes in cluster E
K02D10.1 Aff_K02D10.1 P W All gene names: K02D10.1; K02D10.1b.1; K02D10.1b.2;
3J865; CE17151; CE29423; WBGene00019301; WP:CE17151;
WP:CE29423
WormBase description: 4-NITROPHENYLPHOSPHATASE
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
K02D3.1 Aff_K02D3.1 P W All gene names: K02D3.1; CE06069; WBGene00010504;
WP:CE06069; XO323
K02G10.8 Aff_K02G10.8 P W All gene names: dnj-14; K02G10.8; CE04708; NM_076405;
WBGene00001032; WP:CE04708; XF330
WormBase description: This gene encodes a protein
containing a DnaJ ('J') domain.
Member of lists (Publications lists):
Lund et al 2002 Fig3B neuro-specific
genes, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated
K03D10.1 Aff_K03D10.1 P W All gene names: kal-1; K03D10.1; 1O722; CE35892;
NM_061067; WBGene00002181; WP:CE35892
WormBase description: kal-1 encodes a cell surface
protein that contains a WAP-type protease inhibitor
domain and Type III fibronectin domains and is the C.
elegans ortholog of human KAL-1, mutated in the
X-linked form of the neurological disorder Kallmann
syndrome; in C. elegans, both kal-1 loss-of-function
mutations and kal-1 overexpression result in similar
phenotypes that indicate KAL-1 activity is required for
epithelial morphogenesis and axon branching; kal-1
transcriptional reporters reveal expression beginning
in the 50-cell stage embryo in 2-3 cells with later
embryonic expression in at least 8-10 AB-derived
ventral neuroblasts that are a substrate for migrating
epidermal cells during ventral enclosure; later
expression in larvae and adults is restricted to
anterior neurons, including AIY, AIZ, RID, M5, ASI, and
labial sensory neurons, ventral nerve cord
motorneurons, midbody neurons HSN, CAN, and PVM, tail
neurons DVB, DVC, and PDB, and the nonneuronal
excretory cell as well as in uterine muscles; in the
AIY interneurons, kal-1 is part of a gene battery whose
expression is under the control of the CEH-10 and TTX-3
Paired and LIM-type homeodomains, respectively.
WormBase CDS description: WAP-type (Whey Acidic
Protein) 'four-disulfide core', Fibronectin type III
domain (3 domains)
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
daf-16 Resveratrol
K04G2.6 Aff_K04G2.6 P W All gene names: K04G2.6; K04G2.6.1; K04G2.6.2; 1I619;
CE06100; WBGene00010565; WP:CE06100
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster F,
Reinke et al 2004, fem1 enriched genes, Reinke et al
2004, list of genes in cluster order, Reinke et al
2004, mixed oogenesis soma, Reinke et al 2004, wt herm
vs wt male enriched gen, ViswanathanM et al 2005 S2
sir-2.1 regulated
K05C4.2 Aff_K05C4.2 P W All gene names: K05C4.2; K05C4.2.1; K05C4.2.2; 1P312;
CE19970; WBGene00010579; WP:CE19970
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
K07B1.5 Aff_K07B1.5 P W All gene names: acl-14; K07B1.5; K07B1.5a.1;
K07B1.5a.2; 5J808; CE29507; CE30091; NM_073010;
NM_073011; WBGene00019465; WP:CE29507; WP:CE30091
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, wt herm vs wt male enriched
gen, Reinke et al 2004, mixed oogenesis soma,
ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
K07C5.1 Aff_K07C5.1 P W All gene names: arx-2; K07C5.1; 5K816; CE06111;
NM_073256; WBGene00000200; WP:CE06111
WormBase description: actin
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke
et al 2004, mixed oogenesis soma, ViswanathanM et al
2005 S2 sir-2.1 regulated
K08D10.4 Aff_K08D10.4 P W All gene names: rnp-2; K08D10.4; 4E937; CE28597;
NM_068103; WBGene00004385; WP:CE28597
WormBase description: U1 small nuclear
ribonucleoprotein A
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, wt vs glp-4 enriched genes,
Reinke et al 2004, oogenesis enriched genes, Reinke et
al 2004, wt herm vs wt male enriched gen, ViswanathanM
et al 2005 S2 sir-2.1 regulated
K08F4.2 Aff_K08F4.2 P W All gene names: K08F4.2; 4K892; CE37535;
WBGene00010677; WP:CE37535
WormBase description: RNA recognition motif. (aka RRM,
RBD, or RNP domain)
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, wt vs glp-4 enriched genes,
Reinke et al 2004, oogenesis enriched genes, Reinke et
al 2004, wt herm vs wt male enriched gen, Reinke et al
2004, GO categories, ViswanathanM et al 2005 S2
sir-2.1 regulated
K08H2.6 Aff_K08H2.6 P W All gene names: hpl-1; K08H2.6; CE06164; NM_077798;
WBGene00001995; WP:CE06164; XN865
WormBase description: The hpl-1 gene encodes a homolog
of heterochromatin protein 1 (HP1) that acts to support
the activity of HPL-2 in promoting germline function,
but that by itself is dispensable for any obvious
function in vivo.
WormBase CDS description: murine modifier 2 protein
like
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
K09A9.1 Aff_K09A9.1 P W All gene names: K09A9.1; CE33670; WBGene00010700;
WP:CE33670; XQ229
WormBase description: serine/threonine kinase
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster A, Reinke et al 2004, list of genes in cluster
order
K09A9.2 Aff_K09A9.2 P W All gene names: rab-14; K09A9.2; K09A9.2.1; K09A9.2.2;
CE11974; NM_078171; WBGene00004276; WP:CE11974; XQ224
WormBase description: rab-14 encodes a member of the
Rab GTPase family.
WormBase CDS description: RAS-related protein
Member of lists (Publications lists):
Jones et al 2001 Non dauer genes
P<0.05, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster A,
Reinke et al 2004, fem1 enriched genes, Reinke et al
2004, list of genes in cluster order, Reinke et al
2004, mixed oogenesis soma, Reinke et al 2004, GO
categories, ViswanathanM et al 2005 S2 sir-2.1
regulated
K09H9.7 Aff_K09H9.7 P W All gene names: K09H9.7; 1D718; CE39596;
WBGene00019598; WP:CE39596
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, GO categories, ViswanathanM et al 2005 S2
sir-2.1 regulated
K10B3.5 Aff_K10B3.5 P W All gene names: K10B3.5; CE07368; WBGene00019611;
WP:CE07368; XD722
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
K11H3.1 Aff_K11H3.1 P W All gene names: K11H3.1; K11H3.1b.1; K11H3.1b.2; 3K944;
CE31850; CE31851; WBGene00010778; WP:CE31850;
WP:CE31851
WormBase description: K11H3.1 encodes one of two C.
elegans glycerol 3-phosphate dehydrogenases; although
loss of K11H3.1 activity via large-scale RNAi screens
results in no obvious defects, expression of a K11H3.1
cDNA in Saccharomyces cerevisiae hog1 mutants is able
to rescue the high osmolarity-sensitive growth
phenotype of these mutants, suggesting that K11H3.1
encodes a functional glycerol 3-phosphate
dehydrogenase.
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated
K12F2.2 Aff_K12F2.2 P W All gene names: klp-5; unc-107; vab-8; K12F2.2; 5M705;
CE23870; CE31041; NM_073662; NM_073663; WBGene00006874;
WP:CE23870; WP:CE31041
WormBase description: The vab-8 gene encodes a novel
protein containing an atypical kinesin-like motor
domain that is required for many posteriorly-directed
cell migrations, as well as axonal outgrowth and
pathfinding; vab-8 encodes two protein isoforms:
VAB-8S, a novel protein expressed in migrating cells,
and VAB-8L, which contains a kinesin-related domain, is
expressed in neurons and functions in growth cone
migrations; VAB-8 interacts with UNC-51, a
serine-threonine kinase also required for axon
outgrowth.
WormBase CDS description: kinesin-like protein
M01B2.10 Aff_M01B2.10 P W All gene names: M01B2.10; 5P742; CE16271;
WBGene00010803; WP:CE16271
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
M02A10.3 Aff_M02A10.3 P W All gene names: sli-1; M02A10.3; CE25058; CE27393;
CE37131; NM_075744; WBGene00004829; WP:CE25058;
WP:CE27393; WP:CE37131; XB340
WormBase description: adaptor-like E3 ubiquitin ligase
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
M03F4.7 Aff_M03F4.7 P W All gene names: M03F4.7; CE12368; CE34060;
WBGene00019760; WP:CE12368; WP:CE34060; XF588
WormBase description: calcium binding protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Murphy et al 2003 Fig2 Class2
shorten lifespan, Wang et al 2003 S4 Climbing, Wang et
al 2003 S3 genes pass one-way ANOVA, Wang et al 2003
S4 genes pass two-wayANOVA P0, Zhang et al 2002, T1
mec-3 dependent genes
M88.6 Aff_M88.6 P W All gene names: pan-1; M88.6; 3F655; CE01041; CE23886;
NM_065523; NM_065524; WBGene00003915; WP:CE01041;
WP:CE23886
WormBase description: Leucine-rich repeats
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol, Wang et al 2003 S4 Climbing, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
PAR2.1 Aff_PAR2.1 P W All gene names: PAR2.1; PAR2.1.1; PAR2.1.2; 3J859;
CE00768; WBGene00019800; WP:CE00768
WormBase description: This gene encodes a protein
predicted by Eisenberg and coworkers, with 68%
accuracy, to be mitochondrial.
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, ViswanathanM et
al 2005 S2 sir-2.1 regulated, ViswanathanM et al 2005
S2 daf-16 Resveratrol
R02E12.6 Aff_R02E12.6 P W All gene names: R02E12.6; R02E12.6.1; R02E12.6.2;
CE30099; WBGene00019830; WP:CE30099; XE628
Member of lists (Publications lists):
Jones et al 2001 Dauer specific genes
P<0.05, Jones et al 2001 T3 20 most abundant Dauer,
Wang et al 2003 S8 SAGE genes in the dauer exit
R03A10.4 Aff_R03A10.4 P W All gene names: R03A10.4; R03A10.4a.1; R03A10.4a.2;
R03A10.4b.1; R03A10.4b.2; CE29335; CE37983;
WBGene00010984; WP:CE29335; WP:CE37983; XQ61
WormBase description: gluamine-phenylpyruvate
transaminase
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, list of genes in cluster C,
ViswanathanM et al 2005 S2 sir-2.1 regulated
R06C7.5 Aff_R06C7.5 P W All gene names: R06C7.5; R06C7.5b.1; R06C7.5b.2; 1H824;
CE06248; CE32476; WBGene00011064; WP:CE06248;
WP:CE32476
WormBase description: The R06C7.5 gene encodes an
ortholog of the human gene ADSL, which when mutated
leads to adenylosuccinate lyase deficiency
(OMIM:103050).
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke
et al 2004, mixed oogenesis soma, Reinke et al 2004, GO
categories, ViswanathanM et al 2005 S2 sir-2.1
regulated
R06F6.6 Aff_R06F6.6 P W All gene names: R06F6.6; 2L101; CE01622;
WBGene00011069; WP:CE01622
WormBase description: Homeobox domain
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 daf-16
Resveratrol
R07E4.4 Aff_R07E4.4 P W All gene names: mig-23; R07E4.4; R07E4.4.1; R07E4.4.2;
CE28748; NM_076593; WBGene00003254; WP:CE28748; XG566
WormBase description: guanosine-diphosphatase
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, list of genes in cluster B,
ViswanathanM et al 2005 S2 sir-2.1 regulated
R07E5.7 Aff_R07E5.7 P W All gene names: R07E5.7; R07E5.7.1; R07E5.7.2; 3F510;
CE00672; WBGene00011115; WP:CE00672
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, wt herm vs wt male enriched
gen, Reinke et al 2004, mixed oogenesis soma, Reinke et
al 2004, list of genes in cluster E, ViswanathanM et al
2005 S2 sir-2.1 regulated
R08B4.2 Aff_R08B4.2 P W All gene names: alr-1; sns-10; R08B4.2; CE03536;
WBGene00011138; WBGene00044330; WP:CE03536; XL742
WormBase description: homeobox protein (otd subfamily)
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
daf-16 Resveratrol
R08E3.4 Aff_R08E3.4 P W All gene names: R08E3.4; CE37662; CE37663;
WBGene00019960; WP:CE37662; WP:CE37663; XF426
WormBase description: C2H2-type zinc finger
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 daf-16 Resveratrol
R10E11.1 Aff_R10E11.1 P W All gene names: cbp-1; cep-1; R10E11.1; 3K863; CE21117;
CE28069; NM_066759; NM_066760; WBGene00000366;
WP:CE21117; WP:CE28069
WormBase description: cbp-1 encodes a homolog of the
mammalian transcriptional cofactors CBP (OMIM:600140)
and p300 (E1A-BINDING PROTEIN, 300-KD; OMIM:602700)
that have been shown to possess histone
acetyltransferase activity, and which, when mutated,
lead to Rubinstein-Taybi syndrome (OMIM:180849) and
colorectal cancer (OMIM:114500); at least one splicing
form of CBP-1 exhibits histone acetyltransferase (HAT)
activity in vitro and has a glutamine/asparagine-rich
domain; CBP-1 is required during embryogenesis for
differentiation of all non-neuronal somatic cell types;
CBP-1 is expressed very early in embryogenesis,
suggesting that it may interact with maternally
provided transcription factors, such as SKN-1, to
specific developmental fates.
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
R10E11.8 Aff_R10E11.8 P W All gene names: vha-1; R10E11.8; R10E11.8.1;
R10E11.8.2; R10E11.8.3; 3K871; CE06291; NM_066764;
WBGene00006910; WP:CE06291
WormBase description: vha-1 encodes a 16-kDa
proteolipid of the vacuolar-type H+-ATPase (V-ATPase)
and is required for embryogenesis and for oocyte
ovulation, based on RNAi analysis; expressed in the
excretory cells and the rectum of adult animals as well
as in a pair of cells posterior to the anus.
WormBase CDS description: ATP synthase subunit C (2
domains)
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster C
R11E3.8 Aff_R11E3.8 P W All gene names: dpf-5; R11E3.8; R11E3.8.1; R11E3.8.2;
R11E3.8.3; 4F568; CE29985; NM_068246; WBGene00001058;
WP:CE29985
WormBase description: This gene encodes a protein
predicted by Eisenberg and coworkers, with 52%
accuracy, to be mitochondrial.
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma,
ViswanathanM et al 2005 S2 sir-2.1 regulated
R12C12.1 Aff_R12C12.1 P W All gene names: R12C12.1; R12C12.1a.1; R12C12.1a.2;
2G343; CE02846; CE33434; WBGene00020022; WP:CE02846;
WP:CE33434
WormBase description: R12C12.1 is orthologous to human
GLYCINE DECARBOXYLASE (GLDC; OMIM:238300), which when
mutated leads to glycine encephalopathy.
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, fem3 enriched genes, Reinke
et al 2004, list of genes in cluster C, Reinke et al
2004, mixed sperm soma, Reinke et al 2004, GO
categories, Reinke et al 2004, herm soma enriched
genes, ViswanathanM et al 2005 S2 sir-2.1 regulated,
Wang et al 2003 S3 genes pass one-way ANOVA, Wang et
al 2003 S4 Early genes, Wang et al 2003 S4 genes pass
two-wayANOVA P0
R57.1 Aff_R57.1 P W All gene names: R57.1; R57.1b.1; R57.1b.2; R57.1c.1;
R57.1c.2; R57.1c.3; CE12844; CE30114; CE37270;
WBGene00020082; WP:CE12844; WP:CE30114; WP:CE37270;
XA925
WormBase description: trans-membrane protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, list of genes in cluster C,
ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
R74.6 Aff_R74.6 P W All gene names: R74.6; 3F292; CE01059; WBGene00011280;
WP:CE01059
WormBase description: DOM34 protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, intrinsic, Reinke et al
2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt
herm vs wt male enriched gen, Reinke et al 2004, GO
categories, ViswanathanM et al 2005 S2 sir-2.1
regulated
T03D8.3 Aff_T03D8.3 P W All gene names: sbt-1; T03D8.3; 5V298; CE18921;
WBGene00011392; WP:CE18921
WormBase description: neuroendocrine protein 7B2
Member of lists (Publications lists):
Jiang et al 2001 Fig1 male-enriched
neuronal, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster A,
Reinke et al 2004, list of genes in cluster order, Wang
et al 2003 S5 genes common to feeding ANOVA, Wang et
al 2003 S3 genes pass one-way ANOVA
T03F1.1 Aff_T03F1.1 P W All gene names: T03F1.1; 1E443; CE13096;
WBGene00020184; WP:CE13096
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated, Wang et al 2003 S4 Early genes,
Wang et al 2003 S3 genes pass one-way ANOVA, Wang et
al 2003 S4 genes pass two-wayANOVA P0
T03F1.3 Aff_T03F1.3 P W All gene names: T03F1.3; 1E435; CE13100;
WBGene00020185; WP:CE13100
WormBase description: T03F1.3 is orthologous to the
human gene PHOSPHOGLYCERETE KINASE 1 (PGK1;
OMIM:311800), which when mutated leads to hemolytic
anemia and neurologic disturbances.
WormBase CDS description: phosphoglycerate kinase
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, fem1 enriched genes, Reinke
et al 2004, mixed oogenesis soma, Reinke et al 2004, GO
categories, ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S3 genes pass one-way
ANOVA, Wang et al 2003 S4 Climbing, Wang et al 2003
S4 genes pass two-wayANOVA P0
T04C10.2 Aff_T04C10.2 P W All gene names: epn-1; T04C10.2; CE26820; CE26821;
NM_078057; NM_078058; WBGene00001329; WP:CE26820;
WP:CE26821; XP436
WormBase description: Yeast hypothetical protein
L8167.6 like
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
T05B4.2 Aff_T05B4.2 P W All gene names: nhr-57; T05B4.2; 5E613; CE13195;
NM_071752; WBGene00003647; WP:CE13195
WormBase description: zinc finger protein
Member of lists (Publications lists):
Jones et al 2001 Dauer specific genes
P<0.05, Wang et al 2003 S7 SAGE genes in the dataset,
Wang et al 2003 S8 SAGE genes in the dauer exit
T05E11.5 Aff_T05E11.5 P W All gene names: imp-2; T05E11.5; 4L882; CE06364;
NM_069678; WBGene00011481; WP:CE06364
WormBase description: Yeast YKK0 like
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated,
Wang et al 2003 S5 genes common to feeding ANOVA, Wang
et al 2003 S3 genes pass one-way ANOVA
T05H4.6 Aff_T05H4.6 P W All gene names: phi-21; T05H4.6; T05H4.6.1; T05H4.6.2;
T05H4.6.3; 5G915; CE13279; WBGene00020269; WP:CE13279
WormBase description: eukaryotic peptide chain release
factor subunit 1
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S5 genes common to feeding
ANOVA, Wang et al 2003 S3 genes pass one-way ANOVA
T06E8.1 Aff_T06E8.1 P W All gene names: acl-2; T06E8.1; 5K510; CE06378;
NM_073177; WBGene00011543; WP:CE06378
WormBase description: T06E8.1 is orthologous to the
human gene 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE
2 (LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE, BETA)
(AGPAT2; OMIM:603100), which when mutated leads to
disease; T06E8.1 protein is predicted to be
mitochondrial.
WormBase CDS description: 1-acyl-SN-glycerol-3-phophate
acyltransferase
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated
T07A5.2 Aff_T07A5.2 P W All gene names: T07A5.2; 3L404; CE36501;
WBGene00011555; WP:CE36501
WormBase description: YK10 homolog
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph
T07E3.5 Aff_T07E3.5 P W All gene names: brc-2; T07E3.5; 3H990; CE32718;
NM_066101; WBGene00020316; WP:CE32718
WormBase description: The T07E3.5 gene encodes a single
BRC domain (in residues 12-109) that might promote
double-stranded DNA break repair; eight tandem BRC
domains are encoded by the central coding region of the
human BRCA2 gene, which when mutated leads to
early-onset breast cancer 2 or hereditary male breast
cancer (OMIM:600185).
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, list of genes in cluster order, Reinke et al
2004, wt herm vs wt male enriched gen, Reinke et al
2004, list of genes in cluster E, ViswanathanM et al
2005 S2 sir-2.1 regulated, ViswanathanM et al 2005 S2
daf-16 Resveratrol
T08D10.2 Aff_T08D10.2 P W All gene names: T08D10.2; CE33174; WBGene00011615;
WP:CE33174; XM569
WormBase description: T08D10.2 encodes an ortholog of
the human histone demethylase LSD1 (KIAA0601), and a
paralog of C. elegans SPR-5; similar histone
demethylase homologs are found in human, mouse,
Drosophila, fission yeast, and Arabidopsis; T08D10.2 is
predicted to demethylate histone H3 lysine 4 residues
and act as a transcriptional corepressor.
WormBase CDS description: corticosteroid-binding
protein
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, wt herm vs wt male enriched
gen, Reinke et al 2004, mixed oogenesis soma, Reinke et
al 2004, list of genes in cluster E, ViswanathanM et al
2005 S2 sir-2.1 regulated, ViswanathanM et al 2005 S2
daf-16 Resveratrol
T08G11.4 Aff_T08G11.4 P W All gene names: T08G11.4; T08G11.4.1; T08G11.4.2;
1J480; CE23958; WBGene00011631; WP:CE23958
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, Reinke et al 2004, intrinsic, Reinke et al
2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt
herm vs wt male enriched gen
T09B4.10 Aff_T09B4.10 P W All gene names: chn-1; tag-69; T09B4.10; T09B4.10.1;
T09B4.10.2; 1G758; CE29991; NM_059380; WBGene00000500;
WP:CE29991
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, wt vs glp-4 enriched genes,
Reinke et al 2004, list of genes in cluster order,
Reinke et al 2004, oogenesis enriched genes, Reinke et
al 2004, wt herm vs wt male enriched gen, Reinke et al
2004, list of genes in cluster E
T09B9.4 Aff_T09B9.4 P W All gene names: T09B9.4; T09B9.4.1; T09B9.4.2; CE01652;
WBGene00011645; WP:CE01652; XK390
WormBase description: T09B9.4 is orthologous to the
human gene PUTATIVE CYTOSKELETAL PROTEIN (D10S170;
OMIM:601985), which when mutated leads to disease.
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma,
ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
T10C6.6 Aff_T10C6.6 P W All gene names: T10C6.6; T10C6.6a.1; T10C6.6a.2;
T10C6.6a.3; T10C6.6b.1; T10C6.6b.2; T10C6.6b.3;
T10C6.6b.4; T10C6.6b.5; 5Q507; CE16381; CE23965;
WBGene00011688; WP:CE16381; WP:CE23965
WormBase description: This gene encodes a protein
predicted by Eisenberg and coworkers, with 52%
accuracy, to be mitochondrial.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
T12B3.4 Aff_T12B3.A P W All gene names: T12B3.4; 4I150; CE21179;
WBGene00020447; WP:CE21179
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated
T12D8.2 Aff_T12D8.2 P W All gene names: drr-2; T12D8.2; T12D8.2.1; T12D8.2.2;
3O734; CE16399; WBGene00011730; WP:CE16399
WormBase description: RNA recognition motif. (aka RRM,
RBD, or RNP domain)
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, ViswanathanM et
al 2005 S2 sir-2.1 regulated, Wang et al 2003 S5
genes common to feeding ANOVA, Wang et al 2003 S3
genes pass one-way ANOVA
T14F9.3 Aff_T14F9.3 P W All gene names: T14F9.3; CE07499; WBGene00020509;
WP:CE07499; XC843
WormBase description: T14F9.3 is orthologous to the
human gene CERVICAL CANCER PROTO-ONCOGENE 7 (HEXB;
OMIM:606873), which when mutated leads to disease.
WormBase CDS description: beta-hexosaminidase beta
subunit
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, wt herm vs wt
male enriched gen, Reinke et al 2004, GO categories,
Reinke et al 2004, herm soma enriched genes,
ViswanathanM et al 2005 S2 sir-2.1 regulated
T14F9.5 Aff_T14F9.5 P W All gene names: hlh-7; lin-32; T14F9.5; CE33318;
NM_076009; WBGene00003018; WP:CE33318; XC846
WormBase description: lin-32 encodes a basic
helix-loop-helix transcription factor that is required
for development of several types of neurons, including
the touch receptor neurons and the male sensory ray
neurons.
WormBase CDS description: hlh transcription factor
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
T14G10.2 Aff_T14G10.2 P W All gene names: pxf-1; ra-gef; T14G10.2; T14G10.2a.1;
T14G10.2a.2; T14G10.2b.1; T14G10.2b.2; 4K930; CE28080;
CE28081; PXF; WBGene00004254; WP:CE28080; WP:CE28081
WormBase description: cell division control protein 25
like
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
T14G12.4 Aff_T14G12.4 P W All gene names: fkh-2; T14G12.4; T14G12.4b.1;
T14G12.4b.2; CE04965; CE29342; NM_076243; NM_076244;
WBGene00001434; WP:CE04965; WP:CE29342; XE360
WormBase description: fkh-2 encodes one of 15 forkhead
transcriptional regulators encoded by the C. elegans
genome, and is homologous to Drosophila sloppy-paired
(slp) and the vertebrate Brain Factor 1 (BF-1,
OMIM:164874, expression is restricted to the central
nervous system); by homology, FKH-2 is predicted to
function as a transcription factor that regulates gene
expression during development; while loss of fkh-2
activity via RNA-mediated interference (RNAi) results
only in mild locomotion defects in L1 larvae, further
RNAi experiments indicate that fkh-2 and pes-1, which
encodes another C. elegans forkhead transcription
factor, are required redundantly for completion of
embryonic and larval development; fkh-2 expression,
which partially overlaps that of pes-1, is detected in
embryos in descendants of the D and AB founder cell
lineages.
Member of lists (Publications lists):
Jones et al 2001 Dauer specific genes
P<0.05, McCarroll et al 2004 SFig5 conserved w/ yeast,
McCarroll et al 2004 SFig1-4 conserved w/ Drosoph,
ViswanathanM et al 2005 S2 sir-2.1 regulated, Wang et
al 2003 S7 SAGE genes in the dataset, Wang et al 2003
S8 SAGE genes in the dauer exit
T16H12.5 Aff_T16H12.5 P W All gene names: bath-43; T16H12.5; T16H12.5b.1;
T16H12.5b.2; T16H12.5b.3; 3L182; CE00510; CE29054;
WBGene00011815; WP:CE00510; WP:CE29054
WormBase description: The T16H12.5 gene encodes a
protein with a meprin-associated Traf homology (MATH)
domain that may be involved in apoptosis.
WormBase CDS description: Kruppel-like zinc finger
protein (outside zinc fingers)
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster A, Reinke et al 2004, list of genes in
cluster order, Shen et al 2005 T1 hif-1indepen
hypoxia, ViswanathanM et al 2005 S2 sir-2.1 regulated
T19A5.1 Aff_T19A5.1 P W All gene names: T19A5.1; T19A5.1.1; T19A5.1.2; 5J441;
CE07509; WBGene00020553; WP:CE07509
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, wt vs glp-4 enriched genes,
Reinke et al 2004, oogenesis enriched genes, Reinke et
al 2004, wt herm vs wt male enriched gen, ViswanathanM
et al 2005 S2 sir-2.1 regulated
T20D4.15 Aff_T20D4.15 P W All gene names: T20D4.15; 5D868; CE13806;
WBGene00020620; WP:CE13806
T21B10.1 Aff_T21B10.1 P W All gene names: T21B10.1; 2J221; CE03683;
WBGene00011883; WP:CE03683
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
T21B6.1 Aff_T21B6.1 P W All gene names: dgn-1; T21B6.1; T21B6.1.1; T21B6.1.2;
CE03679; NM_077425; WBGene00000961; WP:CE03679; XL540
T21E3.3 Aff_T21E3.3 P W All gene names: lrp-2; T21E3.3; 1E504; CE28688;
NM_058869; WBGene00003072; WP:CE28688
WormBase description: EGF-like protein
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 daf-16
Resveratrol
T22H2.4 Aff_T22H2.4 P W All gene names: T22H2.4; 1M288; CE14002;
WBGene00011934; WP:CE14002
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
T23B12.3 Aff_T23B12.3 P W All gene names: T23B12.3; 5I947; CE14030;
WBGene00020718; WP:CE14030
WormBase description: This gene encodes a protein
predicted by Eisenberg and coworkers, with 68%
accuracy, to be mitochondrial.
WormBase CDS description: ribosomal protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, intrinsic, Reinke et al
2004, wt vs glp-4 enriched genes, Reinke et al 2004, GO
categories, ViswanathanM et al 2005 S2 sir-2.1
regulated
T23C6.4 Aff_T23C6.4 P W All gene names: T23C6.4; CE07529; WBGene00020726;
WP:CE07529; XR762