Gene name Source Gene ID Annotation Date Added by
AC3.3 Aff_AC3.3 P W All gene names: abu-1; pqn-1; AC3.3; 5K858; CE05133;
NM_073266; WBGene00000024; WP:CE05133
WormBase description: abu-1 encodes a transmembrane
protein with a predicted signal sequence, a
glutamine/asparagine-rich domain and multiple
cysteine-rich repeats (DUF139); abu-1 expression is
induced by blockage of the unfolded-protein response in
the endoplasmic reticulum, and ABU-1 may help protect
the organism from damage by improperly folded nascent
protein.
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster C, ViswanathanM et al 2005 Fig6A Resveratrol,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
AC3.7 Aff_AC3.7 P W All gene names: dod-15; ugt-1; AC3.7; 5K877; CE05137;
NM_073270; WBGene00007072; WP:CE05137
WormBase description: UDP-glucuronosyltransferase
Member of lists (Publications lists):
Kwon et al 2004 T1 late-induction
Ethanol-response, Murphy et al 2003 Fig2 Class1
elongate lifespan, ReichertK et al 2005 T1 xenobiotic
induced UDP-gl, Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, herm soma enriched
genes, Reinke et al 2004, GO categories, Reinke et al
2004, list of genes in cluster B, ViswanathanM et al
2005 S2 sir-2.1 regulated
AFF_B0564.10 Aff_B0564.10 P W
AFF_C09G5.8 Aff_C09G5.8 P W
AFF_C10B5.2 Aff_C10B5.2 P W
AFF_C13B9.1 Aff_C13B9.1 P W
AFF_C25D7.10 Aff_C25D7.10 P W
AFF_F08G12.6 Aff_F08G12.6 P W
AFF_F11D11.9 Aff_F11D11.9 P W
AFF_F17C11.1 Aff_F17C11.1 P W
AFF_F21D9.6 Aff_F21D9.6 P W
AFF_F39D8.2 Aff_F39D8.2 P W
AFF_F40F12.2 Aff_F40F12.2 P W
AFF_F49H12.C Aff_F49H12.C P W
AFF_H20H17.1 Aff_H20H17.1 P W
AFF_H24O09.C Aff_H24O09.C P W
AFF_K08B12.3 Aff_K08B12.3 P W
AFF_K08F11.6 Aff_K08F11.6 P W
AFF_K09D9.D Aff_K09D9.D P W
AFF_M03A1.3 Aff_M03A1.3 P W
AFF_R05F9.12 Aff_R05F9.12 P W
AFF_R11A5.5 Aff_R11A5.5 P W
AFF_R52.10 Aff_R52.10 P W
AFF_T08B6.1 Aff_T08B6.1 P W
AFF_T08G5.7 Aff_T08G5.7 P W
AFF_T21C12.4 Aff_T21C12.4 P W
AFF_T23H2.6 Aff_T23H2.6 P W
AFF_T28A11.14 Aff_T28A11.14 P W
AFF_W02A2.E Aff_W02A2.E P W
AFF_W09G12.3 Aff_W09G12.3 P W
AFF_Y105C5.RR Aff_Y105C5.RR P W
AFF_Y105E8A.P Aff_Y105E8A.P P W
AFF_Y106G6H.10 Aff_Y106G6H.10 P W
AFF_Y106G6H.10_G Aff_Y106G6H.10_G P W
AFF_Y116F11.ZZ17 Aff_Y116F11.ZZ17 P W
AFF_Y119D3_465.L Aff_Y119D3_465.L P W
AFF_Y13C8_223.B Aff_Y13C8_223.B P W
AFF_Y17G9B.D Aff_Y17G9B.D P W
AFF_Y2C2_202.A Aff_Y2C2_202.A P W
AFF_Y40B10A_112.B Aff_Y40B10A_112.B P W
AFF_Y41E3.5 Aff_Y41E3.5 P W
AFF_Y45F10A.3 Aff_Y45F10A.3 P W
AFF_Y47D3A.O Aff_Y47D3A.O P W
AFF_Y49F6A_1689.C Aff_Y49F6A_1689.C P W
AFF_Y50D7_162.A Aff_Y50D7_162.A P W
AFF_Y52B11C.1 Aff_Y52B11C.1 P W
AFF_Y54C5B.1 Aff_Y54C5B.1 P W
AFF_Y55B1B_119.G Aff_Y55B1B_119.G P W
AFF_Y56A3A.W Aff_Y56A3A.W P W
AFF_Y71A12B.A Aff_Y71A12B.A P W
AFF_Y71F9A_262.A Aff_Y71F9A_262.A P W
B0024.14 Aff_B0024.14 P W All gene names: crm-1; B0024.14; B0024.14c.1;
B0024.14c.2; 5K804; CE31276; CE31277; CE31278; CE31279;
CE36907; NM_171529; NM_171530; NM_171531; NM_171935;
WBGene00007103; WP:CE31276; WP:CE31277; WP:CE31278;
WP:CE31279; WP:CE36907
WormBase description: pro-collagen domains
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 daf-16
Resveratrol
B0207.12 Aff_B0207.12 P W All gene names: avr-14; gbr-2; B0207.12; 1G544;
CE26421; CE30227; CE32092; WBGene00000232; WP:CE26421;
WP:CE30227; WP:CE32092
WormBase description: avr-14 encodes an alpha-type
subunit of a glutamate-gated chloride channel
homologous to human GLRA2, which when mutated leads to
hyperekplexia (OMIM:149400); AVR-14 affects sensitivity
to the antiparisitic drug, ivermectin, in parallel with
avr-15 and glc-1 and in a genetic pathway with unc-9;
it functions in the extrapharyngeal nervous system, and
is expressed in a subset of neurons in the ring
ganglia, ventral cord, and some mechanosensory neurons.
B0213.6 Aff_B0213.6 P W All gene names: nlp-31; B0213.6; 5E459; CE16777;
NM_071706; WBGene00003769; WP:CE16777
WormBase description: nlp-31 encodes five predicted
neuropeptide-like proteins; in C. elegans, nlp-31 is
part of the YGGWamide neuropeptide family that also
contains nlp-24, nlp-25, and nlp-27-32; nlp-31 is
expressed in the hypodermis, suggesting that the
peptides it encodes may have a non-neuronal function;
nlp-31 expression is also detected in precomma-stage
embryos; as loss of nlp-31 activity via large-scale
RNAi screens does not result in any obvious
abnormalities, the precise role of the nlp-31-encoded
peptides in development and/or behavior is not yet
known.
Member of lists (Publications lists):
Lund et al 2002 Fig4 Mount 15, Reinke
et al 2004, IVb male soma enriched genes
B0218.3 Aff_B0218.3 P W All gene names: pmk-1; B0218.3; 4I913; CE06686;
NM_068964; WBGene00004055; WP:CE06686
WormBase description: pmk-1 encodes a mitogen-activated
protein kinase (MAPK), orthologous to human p38 MAPK
(OMIM:600289), that is required for eliciting gonadal
programmed cell death in response to Salmonella
enterica infection; PMK-1 lies upstream of CED-9, a
negative regulator of apoptosis, in the programmed cell
death pathway.
WormBase CDS description: ser/thr kinases
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, wt herm vs wt herm enriched
gen, ViswanathanM et al 2005 S2 sir-2.1 regulated
B0228.6 Aff_B0228.6 P W All gene names: B0228.6; 2I44; CE31283; WBGene00015063;
WP:CE31283
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
B0238.1 Aff_B0238.1 P W All gene names: B0238.1; 5F718; CE07691;
WBGene00015067; WP:CE07691
WormBase description: carboxylesterase
Member of lists (Publications lists):
Murphy et al 2003 Fig2 Class1
elongate lifespan, ReichertK et al 2005 T1
B0250.9 Aff_B0250.9 P W All gene names: B0250.9; 5U950; CE36579;
WBGene00007126; WP:CE36579
WormBase description: B0250.9 is orthologous to the
human gene 7-DEHYDROCHOLESTEROL REDUCTASE (DHCR7;
OMIM:602858), which when mutated leads to disease.
WormBase CDS description: sterol reductase
Member of lists (Publications lists):
Lund et al 2002 Fig1 aging-regulated
genes, McCarroll et al 2004 SFig5 conserved w/ yeast
B0252.2 Aff_B0252.2 P W All gene names: asm-1; B0252.2; 2H201; CE30230;
NM_063014; WBGene00000211; WP:CE30230
WormBase description: Spingomyelin phosphodiesterase
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
B0272.1 Aff_B0272.1 P W All gene names: tbb-4; B0272.1; CE00850; NM_077184;
WBGene00006538; WP:CE00850; XK54
WormBase description: tubulin beta chain
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Portman et al 2004 T1 newly found ray-genes
in25c, Portman et al 2004 T1 25 candidate ray genes,
Reinke et al 2004, IVb male soma enriched genes,
ViswanathanM et al 2005 S2 sir-2.1 regulated
B0272.4 Aff_B0272.4 P W All gene names: B0272.4; CE00853; WBGene00007130;
WP:CE00853; XK47
WormBase description: enoyl-CoA hydratase/isomerase
B0285.7 Aff_B0285.7 P W All gene names: B0285.7; 3F453; CE00646;
WBGene00007139; WP:CE00646
WormBase description: Aminopeptidase
Member of lists (Publications lists):
Lund et al 2002 Fig1 aging-regulated
genes, ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
B0285.8 Aff_B0285.8 P W All gene names: ckb-1; B0285.8; 3F455; CE33590;
NM_065478; WBGene00000511; WP:CE33590
WormBase description: choline kinase
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster C, ViswanathanM et al 2005 S2 daf-16
Resveratrol
B0286.4 Aff_B0286.4 P W All gene names: ntl-2; B0286.4; B0286.4a.1; B0286.4a.2;
B0286.4c.1; B0286.4c.2; B0286.4c.3; B0286.4d.1;
B0286.4d.2; B0286.4d.3; B0286.4d.4; B0286.4d.5; 2E664;
CE03864; CE29537; CE29538; CE39662; NM_062371;
NM_062372; NM_062373; WBGene00003825; WP:CE03864;
WP:CE29537; WP:CE29538; WP:CE39662
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
B0303.14 Aff_B0303.14 P W All gene names: B0303.14; 3J804; CE00003;
WBGene00015132; WP:CE00003
WormBase description: Giant secretory protein I-C
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
B0303.2 Aff_B0303.2 P W All gene names: B0303.2; 3J775; CE00536;
WBGene00015124; WP:CE00536
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S4 Climbing, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
B0303.8 Aff_B0303.8 P W All gene names: sdz-1; B0303.8; 3J788; CE00001;
WBGene00015129; WP:CE00001
Member of lists (Publications lists):
Romagnolo et al 2002 Fig3b Unkown
B0310.2 Aff_B0310.2 P W All gene names: B0310.2; B0310.2.1; B0310.2.2; CE03875;
WBGene00015138; WP:CE03875; XB120
WormBase description: C2H2-type zinc fingers
B0310.4 Aff_B0310.4 P W All gene names: B0310.4; CE03877; WBGene00015140;
WP:CE03877; XB132
WormBase description: repetitive proline-rich cell wall
protein
B0391.9 Aff_B0391.9 P W All gene names: B0391.9; 5Q70; CE17337; WBGene00007164;
WP:CE17337
B0462.3 Aff_B0462.3 P W All gene names: fbxb-119; B0462.3; 5S797; CE15556;
WBGene00007182; WP:CE15556
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, mixed oogenesis soma, Reinke
et al 2004, list of genes in cluster E, ViswanathanM et
al 2005 S2 daf-16 Resveratrol
B0464.5 Aff_B0464.5 P W All gene names: rsk-1; spk-1; srk-1; B0464.5;
B0464.5b.1; B0464.5b.2; B0464.5c.1; B0464.5c.2; 3K551;
CE20457; CE36373; CE36580; NM_066679; WBGene00004980;
WP:CE20457; WP:CE36373; WP:CE36580
WormBase description: spk-1 encodes a serine/threonine
kinase orthologous to the highly conserved
serine/arginine-rich protein kinases (SRPKs) that
phosphorylate SR proteins, essential components of the
pre-mRNA splicing machinery; SPK-1, required for
embryogenesis and germline development, can directly
bind and phosphorylate RSP-3 (CeSF2/ASF), an SR
splicing factor homolog; SPK-1 is expressed
predominantly in the adult germline; SPK-1 is
homologous to human RSK2, which when mutated leads to
Coffin-Lowry syndrome (OMIM:303600).
WormBase CDS description: Eukaryotic protein kinase
domain
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
B0491.1 Aff_B0491.1 P W All gene names: B0491.1; 2L639; CE02103;
WBGene00007189; WP:CE02103
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster F,
Reinke et al 2004, list of genes in cluster order,
Reinke et al 2004, intrinsic, Reinke et al 2004, wt vs
glp-4 enriched genes, Reinke et al 2004, wt herm vs wt
male enriched gen, ViswanathanM et al 2005 S2 sir-2.1
regulated
B0507.1 Aff_B0507.1 P W All gene names: B0507.1; 5J259; CE28815;
WBGene00015218; WP:CE28815
Member of lists (Publications lists):
Wang et al 2003 S3 genes pass
one-way ANOVA, Wang et al 2003 S4 LateList, Wang et al
2003 S4 genes pass two-wayANOVA P0
B0563.1 Aff_B0563.1 P W All gene names: B0563.1; CE02439; WBGene00015261;
WP:CE02439; XJ787
B0563.8 Aff_B0563.8 P W All gene names: B0563.8; CE39467; WBGene00015265;
WP:CE39467; XJ788
C01B12.2 Aff_C01B12.2 P W All gene names: C01B12.2; 2A311; CE39124;
WBGene00015285; WP:CE39124
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
C01F1.3 Aff_C01F1.3 P W All gene names: phi-41; C01F1.3; C01F1.3a.1;
C01F1.3a.2; 2E587; CE06744; CE39553; WBGene00015298;
WP:CE06744; WP:CE39553
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster B, Romagnolo et al 2002 Fig3b Metabolism,
ViswanathanM et al 2005 S2 sir-2.1 regulated, Wang et
al 2003 S4 Climbing, Wang et al 2003 S3 genes pass
one-way ANOVA, Wang et al 2003 S4 genes pass
two-wayANOVA P0
C01F4.2 Aff_F57C9.8 P W All gene names: C01F4.2; 1F420; CE30414; CE33358;
WBGene00015303; WP:CE30414; WP:CE33358
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
C01G10.9 Aff_C01G10.9 P W All gene names: C01G10.9; 5P563; CE07818;
WBGene00007236; WP:CE07818
WormBase description: Initiation factor 2 subunit
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, list of genes in cluster C,
Romagnolo et al 2002 Fig3b Unkown, ViswanathanM et al
2005 S2 sir-2.1 regulated, Wang et al 2003 S4 Early
genes, Wang et al 2003 S3 genes pass one-way ANOVA,
Wang et al 2003 S4 genes pass two-wayANOVA P0
C01G8.9 Aff_C01G8.7 P W All gene names: C01G8.9; 1F870; CE30415; CE33359;
WBGene00015314; WP:CE30415; WP:CE33359
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma
C02B8.2 Aff_C02B8.2 P W All gene names: C02B8.2; CE03891; WBGene00015321;
WP:CE03891; XI761
C02B8.6 Aff_C02B8.6 P W All gene names: C02B8.6; CE29656; WBGene00015324;
WP:CE29656; XI752
WormBase description: DNA repair protein RAD16 (yeast,
weak)
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C02D5.2 Aff_C02D5.2 P W All gene names: C02D5.2; 3J647; CE00034; CE39554;
WBGene00015336; WP:CE00034; WP:CE39554
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster order, Reinke et al 2004, list of genes in
cluster B, Wang et al 2003 S4 Early genes, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
C02F12.1 Aff_C02F12.1 P W All gene names: tsp-17; C02F12.1; CE35213; NM_076233;
WBGene00006643; WP:CE35213; XE303
WormBase description: transpanin
C02F12.7 Aff_C02F12.7 P W All gene names: tag-278; C02F12.7; CE03901;
WBGene00015356; WP:CE03901; XE304
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster A, Reinke et al 2004, list of genes in cluster
order, ViswanathanM et al 2005 S2 sir-2.1 regulated
C05A9.2 Aff_C05A9.2 P W All gene names: C05A9.2; CE05222; WBGene00007317;
WP:CE05222; XL460
Member of lists (Publications lists):
Jones et al 2001 Non dauer genes
P<0.05
C05B5.4 Aff_C05B5.4 P W All gene names: C05B5.4; 3L81; CE00880; WBGene00007321;
WP:CE00880
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C05B5.8 Aff_C05B5.6 P W All gene names: C05B5.8; 3L96; CE33967; WBGene00007324;
WP:CE33967
C05C8.3 Aff_C05C8.3 P W All gene names: dao-1; fkb-3; C05C8.3; 5H707; CE07921;
NM_072434; WBGene00001428; WP:CE07921
WormBase description: fkb-3 encodes a peptidylprolyl
cis/trans isomerase homologous to mammalian FK506
immunosuppressant-binding protein 9; FKB-3 expression
is positively regulated by signaling through the DAF-2
insulin receptor-like pathway and the activity of the
DAF-16 fork-head transcription factor suggesting that
FKB-3 could play a role in metabolism and longevity;
however, as loss of FKB-3 function via RNA-mediated
interference (RNAi) does not result in any
abnormalities, the precise role of FKB-3 in C. elegans
development and/or behavior is not yet known; FKB-3
contains a predicted endoplasmic reticulum (ER)
retention sequence and is thus proposed to localize to
the ER.
WormBase CDS description: FKBP-binding protein
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster B, Wang et al 2003 S4 Climbing, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
C05D10.3 Aff_C05D10.3 P W All gene names: C05D10.3; 3H174; CE29170;
WBGene00015479; WP:CE29170
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
C05D11.13 Aff_C05D11.13 P W All gene names: C05D11.13; 3H532; CE03930;
WBGene00015488; WP:CE03930
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C05D11.5 Aff_C05D11.5 P W All gene names: C05D11.5; 3H496; CE01135;
WBGene00015483; WP:CE01135
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, mixed sperm
soma, Reinke et al 2004, fem3 enriched genes,
ViswanathanM et al 2005 S2 sir-2.1 regulated, Wang et
al 2003 S4 Climbing, Wang et al 2003 S3 genes pass
one-way ANOVA, Wang et al 2003 S4 genes pass
two-wayANOVA P0
C05D11.7 Aff_C05D11.7 P W All gene names: C05D11.7; C05D11.7a.1; C05D11.7a.2;
3H506; CE29663; CE30480; WBGene00015484; WP:CE29663;
WP:CE30480
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster F, Reinke et al 2004, list of genes in
cluster order
C05D12.4 Aff_C05D12.4 P W All gene names: C05D12.4; 2L721; CE02972;
WBGene00007341; WP:CE02972
Member of lists (Publications lists):
Wang et al 2003 S5 genes common to
feeding ANOVA, Wang et al 2003 S3 genes pass one-way
ANOVA
C05D12.5 Aff_C05D12.5 P W All gene names: C05D12.5; 2L723; CE02973;
WBGene00007342; WP:CE02973
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C05D9.3 Aff_C05D9.3 P W All gene names: C05D9.3; CE35381; WBGene00015472;
WP:CE35381; XB733
C05E4.1 Aff_C05E4.1 P W All gene names: pes-21; C05E4.1; 5B243; CE07935;
NM_070917; WBGene00005643; WP:CE07935
WormBase description: srp-2 encodes an ovalbumin-like
serpin (ov-serpin) member of the serine protease
inhibitor superfamily that is orthologous to human
NEUROSERPIN (OMIM:602445, mutated in familial
encephalopathy with neuroserpin inclusion bodies);
SRP-2 is predicted to function as a suicide substrate
that inhibits the proteolytic activity of serine
proteases, and in vitro, recombinant SRP-2 is able to
inhibit granzyme B activity; however, as loss of srp-2
function via RNA-mediated interference (RNAi) does not
result in any obvious abnormalities, the precise role
of SRP-2 in C. elegans development and/or behavior is
not yet known; srp-2 expression is detected in
hypodermal cells, particularly in the lateral seam
cells.
WormBase CDS description: serine protease inhibitor
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster order, Wang et al 2003 S6 removed genes of
contamination
C05E4.9 Aff_H24O09.A P W All gene names: gei-7; C05E4.9; C05E4.9a.1; C05E4.9a.2;
C05E4.9a.3; C05E4.9b.1; C05E4.9b.2; 5B204; CE23521;
CE32565; NM_070905; WBGene00001564; WP:CE23521;
WP:CE32565
WormBase description: gei-7 encodes a predicted
isocitrate lyase/malate synthase, an enzyme known to
function in the glyoxylate cycle; GEI-7 was identified
in a screen for proteins that interact with GEX-3, a
homolog of human HEM-2 which is required for embryonic
development; GEI-7 is required for embryonic
morphogenesis and appears to act downstream of DAF-16
to influence lifespan.
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, Murphy et al 2003 Fig2 Class1 elongate
lifespan, ViswanathanM et al 2005 S2 sir-2.1 regulated
C05G5.3 Aff_C05G5.3 P W All gene names: C05G5.3; CE30853; WBGene00007349;
WP:CE30853; XP370
C06B8.7 Aff_C06B8.7 P W All gene names: C06B8.7; 5P989; CE30854;
WBGene00007372; WP:CE30854
WormBase description: Human M130 antigen like protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Romagnolo et al 2002 Fig3b
Unkown, ViswanathanM et al 2005 S2 sir-2.1 regulated
C06C3.1 Aff_C06C3.1 P W All gene names: mel-11; C06C3.1; 2J657; CE20486;
CE32566; CE32567; CE36682; NM_063593; WBGene00003196;
WP:CE20486; WP:CE32566; WP:CE32567; WP:CE36682
WormBase description: ankyrin-like repeats
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster F, Reinke et al 2004, list of genes in
cluster order
C06E1.10 Aff_C06E1.10 P W All gene names: rha-2; C06E1.10; 3J700; CE29563;
WBGene00015525; WP:CE29563
WormBase description: The C06E1.10 gene encodes a DEAH
helicase orthologous to the Drosophila KURZ, the human
KIAA1517, and the S. cerevisiae ECM16 proteins.
WormBase CDS description: ATP-dependent RNA helicase
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph
C06G4.2 Aff_C06G4.2 P W All gene names: clp-1; C06G4.2; C06G4.2a.1; C06G4.2a.2;
C06G4.2b.1; C06G4.2b.2; C06G4.2b.3; 3J75; CE00517;
CE30486; CE37743; CE37744; NM_066339; NM_066340;
NM_171201; NM_171886; WBGene00000542; WP:CE00517;
WP:CE30486; WP:CE37743; WP:CE37744
WormBase description: clp-1 encodes a calpain homolog
that has significant identity to mammalian calpains
over its whole length and that contains motifs typical
of calpains, including a thiol (cysteine) protease
active site and a Ca[2+]-binding domain; CLP-1 is
required, in parallel with TRA-3 but in series with
ASP-3 and ASP-3, for degenerative (necrotic-like) cell
death in neurons induced by mutations such as mec-4(d),
deg-3(d), or gsa-1(gf).
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
C06G8.1 Aff_C06G8.1 P W All gene names: C06G8.1; 4L544; CE05229;
WBGene00007384; WP:CE05229
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster C, Reinke et al 2004, wt herm vs wt herm
enriched gen, ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S3 genes pass one-way
ANOVA, Wang et al 2003 S4 Dauer Enriched, Wang et al
2003 S4 genes pass two-wayANOVA P0
C07A9.6 Aff_C07A9.6 P W All gene names: ugt-60; C07A9.6; C07A9.6.1; C07A9.6.2;
3K766; CE33970; WBGene00007402; WP:CE33970
WormBase description: UDP-glucuronosyltransferase
C07B5.5 Aff_C07B5.5 P W All gene names: nuc-1; C07B5.5; CE00895; NM_077203;
WBGene00003828; WP:CE00895; XK159
WormBase description: The nuc-1 gene encodes a DNase II
homolog similar to mammalian and Drosophila DNaseII
enzymes and is required for DNA degradation during
apoptosis as well as for degradation of dietary DNA
during normal feeding; during apoptosis, NUC-1
functions in apoptotic cells at an intermediate stage
of DNA degradation, after the killing step, but prior
to cell-corpse engulfment.
Member of lists (Publications lists):
Golden et al 2004, daf-2
differentially expressed , McCarroll et al 2004
SFig1-4 conserved w/ Drosoph, ViswanathanM et al 2005
S2 sir-2.1 regulated
C08B11.3 Aff_C08B11.3 P W All gene names: C08B11.3; 2I314; CE01473;
WBGene00007433; WP:CE01473
WormBase description: Zinc finger, C2H2 type
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster F, Reinke et al 2004, fem1 enriched genes,
Reinke et al 2004, list of genes in cluster order,
Reinke et al 2004, mixed oogenesis soma, Reinke et al
2004, wt herm vs wt male enriched gen, Reinke et al
2004, GO categories, ViswanathanM et al 2005 S2 daf-16
Resveratrol, ViswanathanM et al 2005 S2 sir-2.1
regulated
C08F1.3 Aff_C08F1.3 P W All gene names: fbxb-13; C08F1.3; 2C79; CE08018;
WBGene00015607; WP:CE08018
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; its encoded
protein also contains a Pfam-B45 motif of presently
unknown function.
C08F1.6 Aff_C08F1.6 P W All gene names: C08F1.6; 2C78; CE08021; WBGene00015610;
WP:CE08021
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster E, ViswanathanM et al 2005 S2 daf-16
Resveratrol
C08F1.8 Aff_C08F1.8 P W All gene names: C08F1.8; 2C92; CE08023; WBGene00015611;
WP:CE08023
WormBase description: reverse transcriptase
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 daf-16
Resveratrol
C08F8.4 Aff_C08F8.4 P W All gene names: C08F8.4; 4L922; CE05251;
WBGene00007446; WP:CE05251
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, spermatogenesis
enriched genes, Reinke et al 2004, wt herm vs wt herm
enriched gen, Reinke et al 2004, fem3 enriched genes,
Reinke et al 2004, wt vs glp-4 enriched genes, Reinke
et al 2004, wt males vs glp4 male enriched , Reinke et
al 2004, list of genes in cluster D, Reinke et al 2004,
shared sperm
C08F8.5 Aff_C08F8.5 P W All gene names: fbxb-9; C08F8.5; 4L924; CE05252;
WBGene00007447; WP:CE05252
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; its encoded
protein also contains a Pfam-B45 motif of presently
unknown function.
Member of lists (Publications lists):
Murphy et al 2003 Fig2 Class2 shorten
lifespan, Reinke et al 2004, list of genes in cluster
order, ViswanathanM et al 2005 S2 daf-16 Resveratrol
C08F8.8 Aff_C08F8.8 P W All gene names: nhr-67; C08F8.8; 4L939; CE18491;
NM_069693; WBGene00003657; WP:CE18491
WormBase description: nuclear hormone receptor
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
C09B8.4 Aff_C09B8.4 P W All gene names: C09B8.4; CE30242; WBGene00015623;
WP:CE30242; XG638
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C09B9.1 Aff_C09B9.1 P W All gene names: C09B9.1; 4F805; CE06793;
WBGene00015626; WP:CE06793
Member of lists (Publications lists):
Jones et al 2001 Dauer specific genes
P<0.05, Wang et al 2003 S7 SAGE genes in the dataset,
Wang et al 2003 S8 SAGE genes in the dauer exit
C09D4.2 Aff_C09D4.2 P W All gene names: C09D4.2; 1G59; CE08031; WBGene00015633;
WP:CE08031
Member of lists (Publications lists):
Baugh et al 2005, validated PAL-1
target genes, Baugh et al 2005, PAL-1 target genes,
Reinke et al 2004, list of genes in cluster A, Reinke
et al 2004, list of genes in cluster order,
ViswanathanM et al 2005 S2 sir-2.1 regulated
C09G5.4 Aff_C09G5.4 P W All gene names: col-39; C09G5.4; 2K995; CE01484;
NM_063908; WBGene00000616; WP:CE01484
WormBase description: col-39 encodes a collagen that is
individually dispensable for viability and gross
morphology in mass RNAi screens; the amino- and
carboxyl-terminal cysteine-rich regions of COL-39 are
most closely related to those of COL-8, COL-19, and
COL-35.
WormBase CDS description: collagen
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster C, Reinke et al 2004, wt herm vs wt herm
enriched gen, ViswanathanM et al 2005 S2 sir-2.1
regulated
C09H6.2 Aff_C09H6.2 P W All gene names: lin-10; C09H6.2; 1I686; CE15610;
CE27060; NM_059825; WBGene00002999; WP:CE15610;
WP:CE27060
WormBase description: The lin-10 gene encodes a PDZ and
PTB domain-containing protein that is homologous to
mammalian Munc interacting proteins (Mint1,
OMIM:602414) and is required for polarized protein
localization; LIN-10 is required for proper
localization of the LET-23 EGF receptor to the
basolateral membrane of the vulval precursor cells and
for proper postsynaptic localization of GLR-1, an
AMPA-type glutamate receptor in interneurons; LIN-10 is
detected in the cytoplasm, membrane, and at
particularly high levels in the Golgi.
WormBase CDS description: Phosphotyrosine interaction
domain (PTB/PID)., PDZ domain (Also known as DHR or
GLGF). (2 domains)
C10A4.3 Aff_C10A4.3 P W All gene names: C10A4.3; CE02471; WBGene00015664;
WP:CE02471; XI19
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C10C5.3 Aff_C10C5.3 P W All gene names: C10C5.3; 4K139; CE03011;
WBGene00007507; WP:CE03011
WormBase description: aminoacylase-1
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster order, Reinke et al 2004, list of genes in
cluster C, ViswanathanM et al 2005 S2 sir-2.1
regulated
C10C5.5 Aff_C10C5.5 P W All gene names: C10C5.5; 4K147; CE36099;
WBGene00007509; WP:CE36099
WormBase description: aminoacylase-1
Member of lists (Publications lists):
Murphy et al 2003 Fig2 Class2 shorten
lifespan, Reinke et al 2004, GO categories, Reinke et
al 2004, IVb male soma enriched genes, ViswanathanM et
al 2005 S2 sir-2.1 regulated
C10C6.3 Aff_C10C6.3 P W All gene names: C10C6.3; 4M226; CE35392;
WBGene00007512; WP:CE35392
Member of lists (Publications lists):
Reinke et al 2004, herm sperm, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, spermatogenesis enriched genes, Reinke et al
2004, fem3 enriched genes
C10E2.4 Aff_C10E2.4 P W All gene names: C10E2.4; CE08063; WBGene00015674;
WP:CE08063; XR360
C10F3.4 Aff_C10F3.4 P W All gene names: C10F3.4; 5G449; CE30723; CE37609;
WBGene00015678; WP:CE30723; WP:CE37609
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
daf-16 Resveratrol, Wang et al 2003 S3 genes pass
one-way ANOVA, Wang et al 2003 S4 Dauer Enriched, Wang
et al 2003 S4 genes pass two-wayANOVA P0
C10G8.6 Aff_C10G8.6 P W All gene names: ceh-34; C10G8.6; 5F794; CE20496;
NM_072018; WBGene00000455; WP:CE20496
WormBase description: ceh-34 encodes a homeodomain
protein, homologous to human SIX2 (OMIM:604994), that
is expressed very weakly in the pharynxes of late
embryos and early larvae; it has no known function.
WormBase CDS description: homeobox protein
C10H11.3 Aff_C10H11.3 P W All gene names: ugt-25; C10H11.3; 1F303; CE08092;
WBGene00015692; WP:CE08092
WormBase description: 7TM chemoreceptor, ugt family
Member of lists (Publications lists):
Kwon et al 2004 T1 late-induction
Ethanol-response, Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster C, Reinke et al 2004, mixed sperm soma, Reinke
et al 2004, GO categories, Reinke et al 2004, fem3
enriched genes
C11G6.2 Aff_C11G6.2 P W All gene names: C11G6.2; CE05256; WBGene00007523;
WP:CE05256; XQ943
WormBase description: helicase like
C11G6.4 Aff_C11G6.4 P W All gene names: nhr-28; C11G6.4; C11G6.4a.1;
C11G6.4a.2; C11G6.4b.1; C11G6.4b.2; C11G6.4b.3;
CE27061; CE37954; WBGene00003624; WP:CE27061;
WP:CE37954; XQ973
WormBase description: nuclear hormone receptor, nhr-28
C11H1.7 Aff_C11H1.7 P W All gene names: C11H1.7; CE18492; WBGene00007531;
WP:CE18492; XO945
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
C11H1.9 Aff_C11H1.5 P W All gene names: C11H1.9; CE05264; CE37316;
WBGene00023500; WP:CE05264; WP:CE37316; XO938
Member of lists (Publications lists):
Wang et al 2003 S4 Climbing, Wang et
al 2003 S3 genes pass one-way ANOVA, Wang et al 2003
S4 genes pass two-wayANOVA P0
C13B7.5 Aff_Y45G12C.G P W All gene names: str-119; C13B7.5; C13B7.A; 5C904;
CE20503; NM_071265; WBGene00006170; WP:CE20503
WormBase description: 7TM chemoreceptor, str family
C13C12.2 Aff_C13C12.2 P W All gene names: C13C12.2; 5N4; CE08133; WBGene00007552;
WP:CE08133
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster B, Romagnolo et al 2002 Fig3b Unkown,
ViswanathanM et al 2005 S2 daf-16 Resveratrol, Wang et
al 2003 S3 genes pass one-way ANOVA, Wang et al 2003
S4 LateList, Wang et al 2003 S4 genes pass
two-wayANOVA P0
C13G5.1 Aff_C13G5.1 P W All gene names: ceh-16; C13G5.1; 3J715; CE37477;
NM_066497; WBGene00000439; WP:CE37477
WormBase description: ceh-16 encodes a protein that
contains a homeobox domain.
WormBase CDS description: Engrailed homeotic protein
Member of lists (Publications lists):
Baugh et al 2005, PAL-1 target genes,
McCarroll et al 2004 SFig1-4 conserved w/ Drosoph
C14A4.6 Aff_C14A4.6 P W All gene names: C14A4.6; C14A4.6.1; C14A4.6.2; 2K884;
CE02147; WBGene00007557; WP:CE02147
C14B9.6 Aff_C14B9.5 P W All gene names: gei-8; pqn-12; C14B9.6; 3J202; CE29577;
CE30603; CE36784; NM_066371; NM_066372; NM_171207;
WBGene00001565; WP:CE29577; WP:CE30603; WP:CE36784
WormBase description: gei-8 encodes a novel protein
highly similar to C. briggsae BP:CBP04038 that contains
a glutamine/asparagine (Q/N)-rich ('prion') domain (by
the algorithm of Michelitsch and Weissman) and two
myb-like DNA-binding domains; interacts with GEX-3 in
yeast two-hybrid assays.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
C14F11.2 Aff_C14F11.2 P W All gene names: C14F11.2; CE29578; WBGene00015779;
WP:CE29578; XG828
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster A, Reinke et al 2004, list of genes in
cluster order
C14F11.6 Aff_C14F11.6 P W All gene names: C14F11.6; CE02482; WBGene00015781;
WP:CE02482; XG856
WormBase description: DTDP-4-dehydrorhamnose
3,5-epimerase (RFBC gene)
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster A, Reinke et al 2004, list of genes in cluster
order, ViswanathanM et al 2005 S2 sir-2.1 regulated,
Wang et al 2003 S5 genes common to feeding ANOVA, Wang
et al 2003 S3 genes pass one-way ANOVA
C14H10.2 Aff_C14H10.2 P W All gene names: C14H10.2; CE23543; WBGene00007592;
WP:CE23543; XK862
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster A, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, herm soma enriched genes,
ViswanathanM et al 2005 S2 sir-2.1 regulated, Wang et
al 2003 S4 Climbing, Wang et al 2003 S3 genes pass
one-way ANOVA, Wang et al 2003 S4 genes pass
two-wayANOVA P0
C15C8.1 Aff_C15C8.1 P W All gene names: C15C8.1; 5N215; CE05285;
WBGene00007604; WP:CE05285
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 daf-16
Resveratrol
C15H9.10 Aff_C15H9.10 P W All gene names: C15H9.10; CE06836; WBGene00015804;
WP:CE06836; XG730
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster B, ViswanathanM et al 2005 S2 sir-2.1
regulated
C15H9.7 Aff_C15H9.7 P W All gene names: C15H9.7; CE06835; WBGene00015802;
WP:CE06835; XG726
WormBase description: kynureninase
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, Murphy et al 2003 Fig2 Class2 shorten
lifespan, ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S4 Early genes, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
C15H9.8 Aff_C15H9.8 P W All gene names: prx-3; C15H9.8; CE04000; NM_076624;
WBGene00004193; WP:CE04000; XG732
WormBase description: prx-3 is orthologous to the human
gene PEROXISOMAL BIOGENESIS FACTOR 3 (PEX3;
OMIM:603164), which when mutated leads to Zellweger
syndrome of complementation group G.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C16C4.6 Aff_C16C4.6 P W All gene names: fbxb-98; C16C4.6; 2C131; CE08202;
WBGene00015830; WP:CE08202
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; its encoded
protein also contains a Pfam-B45 motif of presently
unknown function.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 daf-16
Resveratrol
C16H3.3 Aff_C16H3.3 P W All gene names: C16H3.3; CE08237; CE27697;
WBGene00015868; WP:CE08237; WP:CE27697; XS216
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster A, Reinke et al 2004, list of genes in cluster
order, ViswanathanM et al 2005 S2 daf-16 Resveratrol
C17B7.3 Aff_C17B7.3 P W All gene names: C17B7.3; 5D823; CE16851;
WBGene00015877; WP:CE16851
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S4 TransientList, Wang et
al 2003 S3 genes pass one-way ANOVA, Wang et al 2003
S4 genes pass two-wayANOVA P0
C17C3.12 Aff_C17C3.12 P W All gene names: acdh-2; C17C3.12; C17C3.12c.1;
C17C3.12c.2; CE29175; CE29176; CE34697; NM_062665;
NM_062666; NM_062667; WBGene00015894; WP:CE29175;
WP:CE29176; WP:CE34697
WormBase description: acyl-CoA dehydrogenase
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C17C3.7 Aff_C17C3.7 P W All gene names: hlh-25; C17C3.7; 2F825; CE04027;
NM_062662; WBGene00001964; WP:CE04027
C17C3.8 Aff_C17C3.8 P W All gene names: hlh-26; C17C3.8; 2F822; CE04028;
NM_062661; WBGene00001965; WP:CE04028
C17D12.7 Aff_C17D12.7 P W All gene names: C17D12.7; 1M196; CE23554;
WBGene00007640; WP:CE23554
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C17G1.3 Aff_C17G1.3 P W All gene names: ugt-23; C17G1.3; CE08282;
WBGene00007650; WP:CE08282; XK542
WormBase description: UDP-glucosyltransferase
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster C, Reinke et al 2004, GO categories, Reinke et
al 2004, herm soma enriched genes, Wang et al 2003 S3
genes pass one-way ANOVA, Wang et al 2003 S4 Dauer
Enriched, Wang et al 2003 S4 genes pass two-wayANOVA
P0
C17G1.7 Aff_C17G1.7 P W All gene names: C17G1.7; C17G1.7.1; C17G1.7.2; CE39223;
WBGene00007653; WP:CE39223; XK572
WormBase description: cysteine synthase
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster A, Reinke et al 2004, list of genes in cluster
order
C18A11.7 Aff_C18A11.7 P W All gene names: dim-1; C18A11.7; C18A11.7b.1;
C18A11.7b.2; C18A11.7b.3; C18A11.7b.4; CE04038;
CE27706; WBGene00001000; WP:CE04038; WP:CE27706; XI670
Member of lists (Publications lists):
Link et al 2003 T2 Abeta repressed,
Reinke et al 2004, list of genes in cluster order,
Reinke et al 2004, list of genes in cluster C
C18D1.1 Aff_C18D1.1 P W All gene names: die-1; C18D1.1; C18D1.1.1; C18D1.1.2;
2K352; CE01501; NM_063774; WBGene00000995; WP:CE01501
WormBase description: die-1 encodes a C2H2 zinc finger
protein containing four fingers, homologous to
CG18265-PA in Drosophila; DIE-1 is autonomously
required in the posterior dorsal hypodermis for
intercalation, for morphogenesis in other embryonic
tissues, and for normal postembryonic growth and vulval
development.
WormBase CDS description: Zinc finger, C2H2 type (3
domains)
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, ViswanathanM et al 2005 S2 daf-16
Resveratrol
C18D11.2 Aff_C18D11.2 P W All gene names: maa-1; C18D11.2; 3M910; CE18513;
NM_067130; WBGene00007680; WP:CE18513
WormBase description: maa-1 encodes a predicted
membrane-associated Acyl-CoA binding protein; loss of
maa-1 activity via RNAi results in no obvious defects.
WormBase CDS description: Acyl CoA binding protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster A, Reinke et al 2004, list of genes in
cluster order, ViswanathanM et al 2005 S2 sir-2.1
regulated
C18G1.2 Aff_C18G1.2 P W All gene names: C18G1.2; 5F251; CE17418;
WBGene00015981; WP:CE17418
WormBase description: GATA transcription factor
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster A, Reinke et al 2004, list of genes in cluster
order, ViswanathanM et al 2005 S2 sir-2.1 regulated
C23F12.1 Aff_B0272.5 P W All gene names: C23F12.1; CE32133; CE32134;
WBGene00016006; WP:CE32133; WP:CE32134; XK45
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster B
C23H4.6 Aff_C23H4.6 P W All gene names: C23H4.6; CE08332; WBGene00007694;
WP:CE08332; XM859
WormBase description: Yeast RAD18 protein like
Member of lists (Publications lists):
Jones et al 2001 Non dauer genes
P<0.05, ViswanathanM et al 2005 S2 daf-16 Resveratrol
C24B5.4 Aff_C24B5.4 P W All gene names: C24B5.4; 5J674; CE37611;
WBGene00016046; WP:CE37611
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
C24H11.2 Aff_C24H11.1 P W All gene names: C24H11.2; 3M880; CE18525;
WBGene00007700; WP:CE18525
WormBase description: Protein phosphatase-1 (PP1)
Member of lists (Publications lists):
Reinke et al 2004, male sperm, Reinke
et al 2004, list of genes in cluster order, Reinke et
al 2004, wt herm vs wt herm enriched gen, Reinke et al
2004, fem3 enriched genes, Reinke et al 2004, wt males
vs glp4 male enriched , Reinke et al 2004, mixed sperm
soma, Reinke et al 2004, list of genes in cluster D,
Reinke et al 2004, GO categories
C24H11.3 Aff_C24H11.3 P W All gene names: tbx-38; C24H11.3; 3M874; CE18526;
NM_067125; WBGene00006557; WP:CE18526
WormBase description: T-box
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma, Reinke
et al 2004, GO categories
C25G6.2 Aff_C25G6.2 P W All gene names: tsp-9; C25G6.2; CE04083; NM_075831;
WBGene00006635; WP:CE04083; XB865
WormBase description: transpanin
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S4 Early genes, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
C25G6.5 Aff_C25G6.5 P W All gene names: C25G6.5; CE04086; WBGene00016110;
WP:CE04086; XB868
WormBase description: G-protein coupled receptor
(family 1)
Member of lists (Publications lists):
Baugh et al 2005, PAL-1 target genes,
McCarroll et al 2004 SFig1-4 conserved w/ Drosoph
C26B9.1 Aff_C26B9.1 P W All gene names: C26B9.1; CE30880; CE34262; NM_076507;
WBGene00016131; WP:CE30880; WP:CE34262
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
C26G2.1 Aff_C26G2.1 P W All gene names: syg-2; C26G2.1; CE19703; NM_078034;
WBGene00007750; WP:CE19703; XP281
WormBase description: syg-2 encodes a transmembrane
protein that is a member of the immunoglobulin
superfamily of proteins; during larval development,
SYG-2 activity is required in vulval epithelial cells
for proper synaptic specificity of the HSNL neuron; in
regulating synapse formation, SYG-2 acts as a guidepost
protein for the SYG-1 receptor that interacts with
SYG-2 and acts within HSNL to regulate synaptic
specificity; a SYG-2::GFP fusion protein is expressed
in the primary vulval cell lineages beginning at the L3
larval stage, with expression increasing during the L4
stage and finally disappearing by adulthood; in
embryos, SYG-2::GFP expression is detected in some head
neurons and body wall muscles, the latter of which also
express the reporter during the L1 and L2 larval
stages.
WormBase CDS description: Immunoglobulin domain ;
Fibronectin type III domain
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
C27C12.6 Aff_C27C12.6 P W All gene names: dmd-4; C27C12.6; CE23560;
WBGene00007776; WP:CE23560; XP476
WormBase description: doublesex protein like
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
C27C7.7 Aff_C27C7.7 P W All gene names: C27C7.7; 1M11; CE18537; WBGene00007769;
WP:CE18537
C27D8.3 Aff_C27D8.3 P W All gene names: C27D8.3; 4N472; CE08422; CE39679;
WBGene00007779; WP:CE08422; WP:CE39679
WormBase description: The C27D8.3 gene encodes a
protein that may be involved in apoptosis.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C28A5.4 Aff_C28A5.4 P W All gene names: ceh-43; C28A5.4; 3F536; CE05325;
NM_065503; WBGene00000463; WP:CE05325
WormBase description: A homeobox protein of the
Distal-less (Dll) class that is required for
development of the anterior hypdermis during embryonic
morphogenesis for cell adhesion; also affects embryonic
and larval viability; it is predominantly expressed in
the head hypdodermis, neuronal support cells and CAN
neurons.
WormBase CDS description: homeobox protein (distal-less
subfamily)
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Portman et al 2004 T1 25
candidate ray genes, Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma
C28C12.7 Aff_C28C12.7 P W All gene names: spp-10; C28C12.7; C28C12.7a.1;
C28C12.7a.2; 4J243; CE29486; CE31323; NM_171399;
NM_171400; WBGene00004995; WP:CE29486; WP:CE31323
WormBase description: spp-10 encodes two protein
isoforms that are orthologous to the human gene
PROSAPOSIN (PSAP; OMIM:176801, mutated in Gaucher
disease and metachromatic leukodystrophy); SPP-10A and
-10B are predicted to have 3 and 4 embedded saposin
sequences, that are likely to be split into individual
saposin peptides by proteolysis; in mammals, saposins
activate the enzymes sphingomyelinphosphodiesterase and
beta-glucosylceramidase; spp-10 has no obvious function
in mass RNAi assays.
WormBase CDS description: 7TM chemoreceptor, spp family
Member of lists (Publications lists):
Baugh et al 2005, validated PAL-1
target genes, Baugh et al 2005, PAL-1 target genes,
Reinke et al 2004, mixed sperm soma, Reinke et al 2004,
fem3 enriched genes, ViswanathanM et al 2005 S2
sir-2.1 regulated
C28G1.4 Aff_C28G1.4 P W All gene names: C28G1.4; CE04121; WBGene00016189;
WP:CE04121; XJ468
WormBase description: zinc finger
C29E4.5 Aff_C29E4.5 P W All gene names: tag-250; C29E4.5; 3J8; CE29682;
CE38589; WBGene00016203; WP:CE29682; WP:CE38589
C29F7.2 Aff_C29F7.2 P W All gene names: C29F7.2; CE35414; WBGene00007811;
WP:CE35414; XO35
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster A, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, mixed sperm soma, Reinke et
al 2004, fem3 enriched genes
C29F7.6 Aff_C29F7.6 P W All gene names: C29F7.6; CE08447; WBGene00007813;
WP:CE08447; XO59
Member of lists (Publications lists):
Romagnolo et al 2002 Fig3b others,
ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
C30G4.3 Aff_C30G4.3 P W All gene names: gcy-11; C30G4.3; CE39901; NM_078354;
WBGene00001537; WP:CE39901; XR660
WormBase description: guanylate cyclase receptor
Member of lists (Publications lists):
Baugh et al 2005, PAL-1 target genes,
ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
C31C9.1 Aff_C31C9.1 P W All gene names: tag-10; C31C9.1; 2N925; CE32597;
CE32598; WBGene00006404; WP:CE32597; WP:CE32598
WormBase description: This gene encodes a protein
predicted by Eisenberg and coworkers, with 52%
accuracy, to be mitochondrial
Member of lists (Publications lists):
Bishop et al 2004 T1 Upregulated in
vhl-1 vs WT, ViswanathanM et al 2005 S2 daf-16
Resveratrol, Wang et al 2003 S4 Early genes, Wang et
al 2003 S3 genes pass one-way ANOVA, Wang et al 2003
S4 genes pass two-wayANOVA P0
C31E10.6 Aff_C31E10.6 P W All gene names: C31E10.6; CE08506; WBGene00007847;
WP:CE08506; XO617
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma,
ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
C31H2.4 Aff_C31H2.4 P W All gene names: C31H2.4; CE04132; WBGene00016294;
WP:CE04132; XF772
WormBase description: C31H2.4 is orthologous to human
4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (HPD; OMIM:276710),
which when mutated leads to tyrosinemia type III;
C31H2.4 is somewhat less similar to human HPD than C.
elegans HPD-1 (to which C31H2.4 is paralogous).
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster C, ViswanathanM et al 2005 S2 sir-2.1
regulated
C32B5.14 Aff_C32B5.14 P W All gene names: C32B5.14; 2B254; CE08522;
WBGene00016307; WP:CE08522
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, mixed oogenesis soma,
ViswanathanM et al 2005 S2 sir-2.1 regulated
C32B5.15 Aff_C32B5.15 P W All gene names: C32B5.15; 2B258; CE08523;
WBGene00016308; WP:CE08523
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins.
C32B5.16 Aff_C32B5.16 P W All gene names: sdz-4; C32B5.16; 2B251; CE08524;
WBGene00016309; WP:CE08524
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster E, ViswanathanM et al 2005 S2 sir-2.1
regulated
C32B5.5 Aff_C32B5.5 P W All gene names: C32B5.5; 2B261; CE34725;
WBGene00016298; WP:CE34725
C32B5.9 Aff_C32B5.9 P W All gene names: C32B5.9; 2B247; CE08517;
WBGene00016302; WP:CE08517
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 daf-16
Resveratrol
C32E8.7 Aff_C32E8.7 P W All gene names: ric-19; C32E8.7; 1E346; CE39089;
NM_058815; WBGene00004368; WP:CE39089
WormBase description: The ric-19 gene encodes an
evolutionarily conserved cytosolic protein involved in
neuroendocrine secretion via association with secretory
vesicles.
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
C33A12.12 Aff_C33A12.12 P W All gene names: C33A12.12; 4K248; CE15665;
WBGene00007887; WP:CE15665
WormBase description: Leucine Rich Repeat (2 copies) (2
domains)
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
C33A12.2 Aff_C33A12.2 P W All gene names: nlp-35; C33A12.2; 4K284; CE05348;
WBGene00007881; WP:CE05348
C33B4.3 Aff_C33B4.3 P W All gene names: tag-67; C33B4.3; 2L676; CE01508;
CE36107; WBGene00006444; WP:CE01508; WP:CE36107
WormBase description: ankyrin and proline rich domains
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
C33C12.5 Aff_C33C12.5 P W All gene names: fbxb-38; C33C12.5; 2C458; CE08553;
WBGene00016337; WP:CE08553
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; its encoded
protein also contains a Pfam-B45 motif of presently
unknown function.
Member of lists (Publications lists):
Reinke et al 2004, mixed sperm soma,
Reinke et al 2004, fem3 enriched genes
C33D12.7 Aff_C33D12.7 P W All gene names: ceh-30; C33D12.7; CE06909; NM_076123;
WBGene00000451; WP:CE06909; XD683
WormBase description: ceh-30 encodes a homeodomain
protein most similar to Drosophila and mammalian BarH1
(OMIM:605211) which function in neuronal cell fate
determination; the precise biological role of CEH-30 in
C. elegans development and/or behavior is not yet
known.
WormBase CDS description: homeobox protien
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
C33D3.1 Aff_C33D3.1 P W All gene names: elt-2; C33D3.1; CE31430; GATA;
NM_077354; WBGene00001250; WP:CE31430; XL101
WormBase description: elt-2 encodes a GATA-type
transcription factor most similar to the vertebrate
GATA4-6 transcription factors required for cardiac and
endoderm development (OMIM:601656, 600576); in C.
elegans, ELT-2 is required redundantly with ELT-7 for
initiating and maintaining terminal differentiation of
the intestine; ELT-2 is expressed solely in the
intestine, beginning embryonically at the 2E-cell stage
and continuing in all intestinal cells throughout the
life of the animal; in the regulatory hierarchy
controlling endoderm development, ELT-2 lies downstream
of the maternal regulators SKN-1 and POP-1 and the
embryonic GATA factors MED-1/-2, and END-1/-3; in turn,
ELT-2, along with ELT-7, likely regulates transcription
of a number of intestine-specific terminal
differentiation genes such as ges-1, ifb-2, pha-4, and
the stress-induced mtl-2; ELT-2 also positively
autoregulates, presumably to ensure maintenance of
intestinal differentiation
WormBase CDS description: zinc finger protein (GATA
type)
C33D9.5 Aff_C33D9.5 P W All gene names: C33D9.5; 4J544; CE37808;
WBGene00007899; WP:CE37808
WormBase description: Yeast RAD50 like protein
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 daf-16
Resveratrol
C33D9.8 Aff_C33D9.8 P W All gene names: C33D9.8; 4J548; CE03048;
WBGene00007901; WP:CE03048
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C33E10.1 Aff_C33E10.1 P W All gene names: C33E10.1; CE34265; WBGene00016345;
WP:CE34265; XR919
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; its encoded
protein also contains a Pfam-B45 motif of presently
unknown function.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
C33F10.7 Aff_C33F10.7 P W All gene names: C33F10.7; C33F10.7b.1; C33F10.7b.2;
2F108; CE04140; CE37751; WBGene00016355; WP:CE04140;
WP:CE37751
WormBase description: esterase and beta-lactamase
Member of lists (Publications lists):
Kwon et al 2004 T1 late-induction
Ethanol-response, Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster B, ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
C34C6.6 Aff_C34C6.6 P W All gene names: PEX-5; prx-5; C34C6.6; 2I995; CE03054;
CE36377; WBGene00004194; WP:CE03054; WP:CE36377
WormBase description: prx-5 encodes an ortholog of the
human receptor for type I peroxisomal targeting signal
protein, PXR1 (or PEX5; OMIM:600414), which when
mutated leads to neonatal adrenoleukodystrophy or
Zellweger syndrome; PXR1 protein is a component of the
peroxisomal import machinery known to exist in
organisms like yeast, plants and mammals.
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, list of genes in cluster B
C34E11.1 Aff_C34E11.1 P W All gene names: rsd-3; C34E11.1; C34E11.1.1;
C34E11.1.2; CE03062; NM_077572; WBGene00004682;
WP:CE03062; XM421
WormBase description: yeast hypothetical L8167.6 like
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster A, Reinke et al 2004, list of genes in
cluster order, ViswanathanM et al 2005 S2 sir-2.1
regulated
C34G6.4 Aff_C34G6.4 P W All gene names: pgp-2; C34G6.4; 1G471; CE29212;
NM_059306; WBGene00003996; WP:CE29212
WormBase description: pgp-2 encodes a member of the ABC
transporter family with highest similarity to the
vertebrate MDR (multidrug resistance) family, and is
orthologous to human MDR1 (ABCB1; OMIM:171050, mutated
in Crohn disease); PGP-2 is expressed at lower levels
during the embryonic stages with higher expression
later in development.
WormBase CDS description: abc transporter
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster order, Reinke et al 2004, list of genes in
cluster C
C34G6.6 Aff_C34G6.6 P W All gene names: noah-1; C34G6.6; C34G6.6a.1;
C34G6.6a.2; 1G452; CE29699; CE30432; WBGene00016422;
WP:CE29699; WP:CE30432
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Wang et al 2003 S3 genes pass
one-way ANOVA, Wang et al 2003 S4 LateList, Wang et al
2003 S4 genes pass two-wayANOVA P0
C34H3.2 Aff_C34H3.A P W All gene names: odd-2; C34H3.2; CE23571; NM_076631;
WBGene00003846; WP:CE23571; XG778
WormBase description: odd-2 encodes a protein with
homology to the Drosophila ODD-SKIPPED family members
and affects larval viability; expressed in the
intestine.
WormBase CDS description: C2H2-type zinc finger protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Romagnolo et al 2002 Fig3b TF
C35C5.1 Aff_C35C5.1 P W All gene names: sdc-2; C35C5.1; CE18542; NM_077523;
WBGene00004746; WP:CE18542; XM151
WormBase description: The sdc-2 gene encodes a protein
that represses transcription of X chromosomes to
achieve dosage compensation, and that also represses
the male sex-determination gene her-1 to elicit
hermaphrodite differentiation.
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma
C35D10.8 Aff_C35D10.8 P W All gene names: C35D10.8; 3F945; CE29702;
WBGene00016445; WP:CE29702
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, list of genes in cluster order
C35D6.3 Aff_C35D6.3 P W All gene names: C35D6.3; 4R99; CE15682; WBGene00007960;
WP:CE15682
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C35E7.3 Aff_C35E7.3 P W All gene names: C35E7.3; 1L415; CE17516;
WBGene00016455; WP:CE17516
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, ViswanathanM et al 2005 S2 sir-2.1
regulated
C35E7.5 Aff_C35E7.5 P W All gene names: C35E7.5; 1L403; CE17518; CE32817;
WBGene00016457; WP:CE17518; WP:CE32817
Member of lists (Publications lists):
Murphy et al 2003 Fig2 Class2 shorten
lifespan, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, wt herm vs wt male enriched
gen, Reinke et al 2004, list of genes in cluster E,
ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
C36E8.3 Aff_C36E8.3 P W All gene names: C36E8.3; 3F99; CE30889; WBGene00007982;
WP:CE30889
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
daf-16 Resveratrol
C36F7.1 Aff_C36F7.1 P W All gene names: irx-1; C36F7.1; 1K114; CE17526;
WBGene00007984; WP:CE17526
WormBase description: Homeobox domain
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
C37E2.4 Aff_C37E2.4 P W All gene names: ceh-36; C37E2.4; CE08623; NM_077964;
WBGene00000457; WP:CE08623; XO802
WormBase description: ceh-36 encodes a paired-like
homeodomain transcription factor that is one of three
orthodenticle (OTD)-like homeodomain proteins in C.
elegans (the others being ttx-1 and ceh-37); CEH-36 is
required broadly for specification of the AWC olfactory
neuron and also for establishing the left-right
asymmetry of the ASEL and ASER gustatory neurons; in
addition, CEH-36 is sufficient to specify the AFD
thermosensory neuron fate in some cell types; CEH-36 is
expressed in the AWC and ASE chemosensory neurons.
WormBase CDS description: Homeobox domain
C37E2.5 Aff_C37E2.5 P W All gene names: ceh-37; C37E2.5; CE08624; NM_077965;
WBGene00000458; WP:CE08624; XO816
WormBase description: ceh-37 encodes one of three C.
elegans proteins with an OTX-like homeodomain; however,
CEH-37 lacks other domains found in OTX proteins, and
the CEH-37 homeodomain is predicted to resemble the Myb
domain of telomere-binding proteins; CEH-37 binds the
telomeric sequence 'TTAGGC' if it is repeated at least
1.5 times, and is mainly localized to the telomere in
vivo; ceh-37 mutants have a weak increase in
chromosomal nondisjunction; CEH-37 is involved in
specifying some aspects of the AWB olfactory neuron
fate, such as expression of an AWB-specific odorant
receptor and a LIM-class homeodomain protein, LIM-4;
CEH-37 is expressed broadly in the early embryo, while
in larvae and adults it is expressed solely in the
excretory cell.
WormBase CDS description: Homeobox domain
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C38C6.4 Aff_C38C6.4 P W All gene names: sre-13; C38C6.4; 2O918; CE38042;
NM_064641; WBGene00007997; WP:CE38042
WormBase description: 7TM receptor, sre family
C39B5.2 Aff_C39B5.C P W All gene names: C39B5.2; 3D325; CE23578;
WBGene00016520; WP:CE23578
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, herm soma enriched
genes
C39E6.4 Aff_C39E6.3 P W All gene names: mls-2; C39E6.4; CE30891; NM_076414;
WBGene00003377; WP:CE30891; XF378
C39F7.2 Aff_C39F7.2 P W All gene names: C39F7.2; C39F7.2.1; C39F7.2.2; 5B704;
CE27581; WBGene00016539; WP:CE27581
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
C40A11.2 Aff_C40A11.2 P W All gene names: C40A11.2; C40A11.2.1; C40A11.2.2;
2C437; CE34742; WBGene00016545; WP:CE34742
C40A11.3 Aff_C40A11.3 P W All gene names: C40A11.3; 2C433; CE19366;
WBGene00016546; WP:CE19366
Member of lists (Publications lists):
Jones et al 2001 Non dauer genes
P<0.05, ViswanathanM et al 2005 S2 sir-2.1 regulated
C40A11.4 Aff_C40A11.4 P W All gene names: C40A11.4; 2C429; CE36797;
WBGene00016547; WP:CE36797
C40A11.7 Aff_C40A11.7 P W All gene names: C40A11.7; 2C438; CE19370;
WBGene00016550; WP:CE19370
C41D11.1 Aff_C41D11.1 P W All gene names: C41D11.1; 1F33; CE08658;
WBGene00016561; WP:CE08658
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
C41H7.1 Aff_C41H7.1 P W All gene names: C41H7.1; 2D307; CE32605;
WBGene00016571; WP:CE32605
C43D7.2 Aff_C43D7.2 P W All gene names: fbxb-65; C43D7.2; 5T805; CE18547;
WBGene00008066; WP:CE18547
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins.
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma
C43D7.8 Aff_Y116F11.I P W All gene names: C43D7.8; 5T784; CE18552;
WBGene00008070; WP:CE18552
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 daf-16
Resveratrol
C44B7.9 Aff_C44B7.9 P W All gene names: pmp-2; C44B7.9; 2H174; CE02547;
NM_063007; WBGene00004059; WP:CE02547
WormBase description: peroxisomal membrane protein
(PMP70, an ATP-binding transport protein)
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster order, Reinke et al 2004, list of genes in
cluster B, ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
C44C10.1 Aff_C44C10.1 P W All gene names: col-180; C44C10.1; CE05408; NM_077559;
WBGene00000753; WP:CE05408; XM332
WormBase description: collagen
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster C, Reinke et al 2004, wt herm vs wt herm
enriched gen, ViswanathanM et al 2005 S2 sir-2.1
regulated
C44C8.1 Aff_C44C8.1 P W All gene names: C44C8.1; 4B655; CE17541;
WBGene00016646; WP:CE17541
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins.
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster A, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, herm soma enriched genes,
ViswanathanM et al 2005 S2 sir-2.1 regulated, Wang et
al 2003 S4 Climbing, Wang et al 2003 S3 genes pass
one-way ANOVA, Wang et al 2003 S4 genes pass
two-wayANOVA P0
C44C8.2 Aff_C44C8.2 P W All gene names: C44C8.2; 4B653; CE17542;
WBGene00016647; WP:CE17542
Member of lists (Publications lists):
Reinke et al 2004, herm soma enriched
genes, ViswanathanM et al 2005 S2 sir-2.1 regulated,
Wang et al 2003 S4 Climbing, Wang et al 2003 S3
genes pass one-way ANOVA, Wang et al 2003 S4 genes
pass two-wayANOVA P0
C44H4.2 Aff_C44H4.2 P W All gene names: sym-5; C44H4.2; CE08723; NM_078024;
WBGene00006370; WP:CE08723; XP197
WormBase description: sym-5 encodes a predicted
transmembrane protein that contains 13 contiguous
leucine-rich repeats (LRRs) and that is similar to
SYM-1, a secreted protein involved in muscle
attachment; sym-5 activity appears to be required for
embryogenesis and functionally overlaps with that of
sym-1 and mec-8 in affecting muscle attachment; in
addition, loss of sym-5 activity via RNA-mediated
interference (RNAi) in a hypersensitized strain
indicates that SYM-5 may also be required for
locomotion, body morphology, and normal rates of
postembryonic growth.
WormBase CDS description: Drosophila chaoptin protein
like
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster B, ViswanathanM et al 2005 S2 daf-16
Resveratrol, Wang et al 2003 S3 genes pass one-way
ANOVA, Wang et al 2003 S4 LateList, Wang et al 2003
S4 genes pass two-wayANOVA P0
C44H4.3 Aff_C44H4.3 P W All gene names: sym-1; C44H4.3; CE08724; NM_078025;
WBGene00006366; WP:CE08724; XP201
WormBase description: sym-1 encodes a protein
containing 15 contiguous leucine-rich repeats (LRRs)
that functionally overlaps with sym-5 and interacts
with mec-8 with respect to embryonic viability and
attachment of body muscle to the extracellular cuticle;
expression begins at the time of embryonic elongation
and SYM-1 is secreted from the apical hypodermal
surface of the embryo
WormBase CDS description: Drosophila chaoptin protein
like
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster B, ViswanathanM et al 2005 S2 daf-16
Resveratrol, Wang et al 2003 S3 genes pass one-way
ANOVA, Wang et al 2003 S4 LateList, Wang et al 2003
S4 genes pass two-wayANOVA P0
C45B11.3 Aff_C45B11.3 P W All gene names: dhs-18; C45B11.3; C45B11.3.1;
C45B11.3.2; 5L526; CE05427; NM_073411; WBGene00000981;
WP:CE05427
WormBase description: alcohol dehydrogenase
Member of lists (Publications lists):
Murphy et al 2003 Fig2 Class1
elongate lifespan, Reinke et al 2004, list of genes in
cluster A, Reinke et al 2004, list of genes in cluster
order
C45E1.1 Aff_C45E1.1 P W All gene names: nhr-64; C45E1.1; 1D677; CE39696;
CE39697; WBGene00003654; WP:CE39696; WP:CE39697
WormBase description: nhr-64 encodes a conserved
nuclear receptor that is a member of the NR2 subfamily
of nuclear receptors that contains Drosophila and human
HNF4 (OMIM:600281, mutations in human HNF4A are
associated with Type I MODY (maturity-onset diabetes of
the young)); by homology, NHR-64 is predicted to
function as a transcription factor that may activate or
repress transcription in response to a hormonal signal;
however, as loss of nhr-64 activity via RNAi does not
result in any obvious abnormalities, the precise role
of NHR-64 in C. elegans development and/or behavior is
not yet known; nhr-64 is broadly expressed and detected
in anterior and posterior neurons, the ventral nerve
cord, the pharynx, gut, and hypodermis.
Member of lists (Publications lists):
Jones et al 2001 Dauer specific genes
P<0.05, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated,
Wang et al 2003 S8 SAGE genes in the dauer exit
C45G9.11 Aff_C45G9.11 P W All gene names: C45G9.11; 3G154; CE27856;
WBGene00016682; WP:CE27856
C46C11.2 Aff_C46C11.2 P W All gene names: C46C11.2; CE39005; CE39006;
WBGene00016705; WP:CE39005; WP:CE39006; XF253
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph
C46G7.1 Aff_C46G7.1 P W All gene names: C46G7.1; C46G7.1.1; C46G7.1.2; 4G783;
CE37213; WBGene00016721; WP:CE37213
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster B
C46H11.9 Aff_C46H11.9 P W All gene names: phat-2; C46H11.9; 1F614; CE08791;
WBGene00016733; WP:CE08791
Member of lists (Publications lists):
Jones et al 2001 Non dauer genes
P<0.05, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, list of genes in cluster B,
ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol, Wang et
al 2003 S3 genes pass one-way ANOVA, Wang et al 2003
S4 LateList, Wang et al 2003 S4 genes pass
two-wayANOVA P0
C47C12.3 Aff_C47C12.3 P W All gene names: C47C12.3; C47C12.3a.1; C47C12.3a.2;
CE33037; CE35437; NM_076907; WBGene00004335;
WP:CE33037; WP:CE35437; XI361
WormBase description: ref-2 is orthologous to the human
gene ZINC FINGER PROTEIN OF CEREBELLUM ZIC2 (ZIC2;
OMIM:603073), which when mutated leads to disease.
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
C47D12.4 Aff_C47D12.4 P W All gene names: C47D12.4; 2L969; CE20568;
WBGene00008138; WP:CE20568
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins.
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
C47E12.8 Aff_C47E12.8 P W All gene names: CeCRMP/DHP-2; dhp-2; C47E12.8; 4K745;
CE05452; NM_069396; WBGene00000964; WP:CE05452
WormBase description: The dhp-2 gene encodes an
ortholog of the human gene DIHYDROPYRIMIDINASE (DPYS),
which when mutated leads to dihydropyrimidinuria
(OMIM:222748).
WormBase CDS description: Ulip like protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, ViswanathanM et al 2005 S2 sir-2.1 regulated,
Wang et al 2003 S4 Climbing, Wang et al 2003 S3
genes pass one-way ANOVA, Wang et al 2003 S4 genes
pass two-wayANOVA P0
C47F8.1 Aff_C47F8.1 P W All gene names: C47F8.1; 1M929; CE17570;
WBGene00008157; WP:CE17570
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C47G2.2 Aff_C47G2.2 P W All gene names: unc-130; C47G2.2; 2L573; CE02166;
NM_064010; WBGene00006853; WP:CE02166
WormBase description: A member of the forkhead domain
family of transcription factors that affects the
generation of the AWA and ASG chemosensory neurons and
is partially required for male tail morphogenesis and
embryogenesis; it is expressed in the AWA and ASG
precursors; it is required for the graded spatial
expression of the UNC-129 TGF-beta guidance factor.
WormBase CDS description: fork head domain protein
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
C48D1.1 Aff_C48D1.1 P W All gene names: C48D1.1; 4N958; CE32833; CE39701;
WBGene00008177; WP:CE32833; WP:CE39701
WormBase description: C.elegans ZYG-11 like protein
Member of lists (Publications lists):
Reinke et al 2004, wt herm vs wt male
enriched gen, Reinke et al 2004, herm soma enriched
genes
C48E7.1 Aff_C48E7.1 P W All gene names: C48E7.1; 1G839; CE08816;
WBGene00016749; WP:CE08816
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S5 genes common to feeding
ANOVA, Wang et al 2003 S3 genes pass one-way ANOVA
C49A1.4 Aff_C49A1.4 P W All gene names: eya-1; C49A1.4; C49A1.4b.1; C49A1.4b.2;
1O814; CE15722; CE36113; WBGene00001377; WP:CE15722;
WP:CE36113
WormBase description: eya-1 encodes a protein
orthologous to Drosophila EYES ABSENT (EYA), human
EYA1, and human EYA4; the human genes EYA1 and EYA4,
when mutated, lead to branchiootorenal dysplasia
syndrome (BOR; OMIM:113650) and autosomal dominant
nonsyndromic sensorineural (late-onset) deafness
(DFNA10; OMIM:601316).
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster order, Reinke et al 2004, list of genes in
cluster E, ViswanathanM et al 2005 S2 sir-2.1
regulated
C50A2.4 Aff_C50A2.4 P W All gene names: C50A2.4; 4B908; CE17582;
WBGene00016798; WP:CE17582
C50B6.9 Aff_C50B6.9 P W All gene names: C50B6.9; 5N819; CE08878;
WBGene00008222; WP:CE08878
C50E10.4 Aff_C50E10.4 P W All gene names: sop-2; C50E10.4; 2M633; CE32334;
NM_064220; WBGene00004945; WP:CE32334
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma
C50F2.1 Aff_C50F2.1 P W All gene names: C50F2.1; 1E461; CE36635;
WBGene00016835; WP:CE36635
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C50F2.4 Aff_C50F2.4 P W All gene names: C50F2.4; 1E456; CE08910;
WBGene00016838; WP:CE08910
C50F2.7 Aff_C50F2.7 P W All gene names: C50F2.7; 1E468; CE08913;
WBGene00016840; WP:CE08913
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C50F4.4 Aff_C50F4.4 P W All gene names: C50F4.4; 5K15b; CE33985;
WBGene00008232; WP:CE33985
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, ViswanathanM et
al 2005 S2 sir-2.1 regulated
C51E3.2 Aff_C51E3.2 P W All gene names: srsx-27; C51E3.2; 5K627; CE33986;
NM_073208; WBGene00008248; WP:CE33986
WormBase description: opoid receptor
C52A10.3 Aff_C52A10.3 P W All gene names: C52A10.3; 5F716; CE17584;
WBGene00016864; WP:CE17584
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
C52B11.2 Aff_C52B11.2 P W All gene names: tag-303; C52B11.2; CE04258;
WBGene00016871; WP:CE04258; XB927
WormBase description: potassium channel protein
Member of lists (Publications lists):
Jones et al 2001 Dauer specific genes
P<0.05, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Wang et al 2003 S7 SAGE genes in the dataset,
Wang et al 2003 S8 SAGE genes in the dauer exit
C52D10.6 Aff_C52D10.6 P W All gene names: skr-12; C52D10.6; 4S111; CE17590;
NM_070644; WBGene00004818; WP:CE17590
WormBase description: skr-12 encodes a homolog of Skp1
in S. cerevisiae, a core component of the SCF (Skp1p,
Cullin, F-box) ubiquitin-ligase complex that
facilitates ubiquitin-mediated protein degradation;
SKR-12 has no known function in vivo, since
skr-12(RNAi) animals are at least superficially normal.
WormBase CDS description: cyclin A-associated protein
Member of lists (Publications lists):
Lund et al 2002 Fig3D Oocyte-en,
ViswanathanM et al 2005 S2 sir-2.1 regulated,
ViswanathanM et al 2005 S2 daf-16 Resveratrol
C52D10.7 Aff_C52D10.7 P W All gene names: skr-9; C52D10.7; 4S107; CE17591;
NM_070642; WBGene00004815; WP:CE17591
WormBase description: skr-9 encodes a homolog of Skp1
in S. cerevisiae, a component of the SCF (Skp1, Cullin,
F-box) ubiquitin-ligase complex that regulates
ubiquitin-mediated protein degradation; SKR-9 is
required for posterior body morphogenesis, embryonic
and larval development, and postembryonic cell
proliferation.
WormBase CDS description: cyclin A-associated protein
Member of lists (Publications lists):
Jones et al 2001 Non dauer genes
P<0.05, Murphy et al 2003 Fig2 Class2 shorten
lifespan, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, intrinsic, Reinke et al 2004,
wt vs glp-4 enriched genes, Reinke et al 2004, wt herm
vs wt male enriched gen, Reinke et al 2004, list of
genes in cluster E, ViswanathanM et al 2005 S2 sir-2.1
regulated
C52D10.8 Aff_C52D10.8 P W All gene names: skr-13; C52D10.8; 4S106; CE17592;
NM_070641; WBGene00004819; WP:CE17592
WormBase description: The skr-13 gene encodes a homolog
of Skp1 in S. cerevisiae that has no known function in
vivo, since skr-13(RNAi) animals are at least
superficially normal.
WormBase CDS description: cyclin A-associated protein
Member of lists (Publications lists):
Kwon et al 2004 T1 late-repression
Ethanol-respon, Lund et al 2002 Fig3D Oocyte-en,
Reinke et al 2004, list of genes in cluster order,
Reinke et al 2004, list of genes in cluster E,
Romagnolo et al 2002 Fig3b Proteases, ViswanathanM et
al 2005 S2 sir-2.1 regulated
C52E2.1 Aff_C52E2.I P W All gene names: fbxb-95; C52E2.1; C52E2.I; 2C127;
CE25826; WBGene00016880; WP:CE25826
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; this gene's
encoded protein also contains an FTH/DUF38 motif, which
may also mediate protein-protein interaction.
Member of lists (Publications lists):
Reinke et al 2004, fem1 enriched
genes, Reinke et al 2004, mixed oogenesis soma
C52E2.2 Aff_C52E2.H P W All gene names: C52E2.2; C52E2.H; 2C125b; CE20597;
WBGene00016881; WP:CE20597
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S3 genes pass one-way
ANOVA, Wang et al 2003 S4 Dauer Enriched, Wang et al
2003 S4 genes pass two-wayANOVA P0
C53C11.4 Aff_C53C11.4 P W All gene names: C53C11.4; CE04267; WBGene00016901;
WP:CE04267; XR923
WormBase description: S. muris microneme antigen
C53H9.2 Aff_C53H9.2 P W All gene names: C53H9.2; C53H9.2b.1; C53H9.2b.2;
C53H9.2b.3; C53H9.2b.4; C53H9.2c.1; C53H9.2c.2;
C53H9.2c.3; C53H9.2c.4; 1C307; CE08963; CE33575;
CE39907; WBGene00016907; WP:CE08963; WP:CE33575;
WP:CE39907
WormBase description: C53H9.2 encodes at least three
protein isoforms orthologous to the GTP-binding
proteins human GNL1 (HSR1; OMIM:143024) and murine
MMR1, as well as LSG1 in S. cerevisiae and many other
eukaryotic and bacterial proteins; one alternative
transcription unit of the C53H9.2 locus, C53H9.2a, has
a natural nonsense transcript that is up-regulated in
vivo by smg[-] mutations, indicating that C53H9.2 is a
natural substrate for SMG-mediated nonsense
suppresssion; C53H9.2 is required in mass RNAi assays
for embryonic viability, normally rapid growth, and
early embryonic nuclear positioning; since several
other natural mRNA substrates of SMG suppression (e.g.,
rpl-3, rpl-8, rpl-10a, rpl-12) have protein products
that are involved in translation, C53H9.2's protein
products may function in translation as well, an
inference supported by the observed role of LSG1 in
cytoplasmic 60S ribosomal subunit biogenesis.
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, intrinsic, Reinke et al
2004, wt vs glp-4 enriched genes, Reinke et al 2004, wt
herm vs wt male enriched gen, ViswanathanM et al 2005
S2 sir-2.1 regulated
C54D1.4 Aff_C54D1.4 P W All gene names: alh-10; C54D1.4; C54D1.4.1; C54D1.4.2;
CE06980; NM_076802; WBGene00000116; WP:CE06980; XH760
WormBase description: aldehyde dehydrogenase
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S4 Climbing, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
C54D1.5 Aff_C54D1.5 P W All gene names: C54D1.5; CE30916; WBGene00016913;
WP:CE30916; XH764
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
C54F6.8 Aff_C54F6.8 P W All gene names: nhr-171; C54F6.8; 5H991; CE17603;
WBGene00016926; WP:CE17603
WormBase description: nuclear hormone receptor
Member of lists (Publications lists):
Baugh et al 2005, validated PAL-1
target genes, Baugh et al 2005, PAL-1 target genes,
ViswanathanM et al 2005 S2 sir-2.1 regulated
C55B6.2 Aff_C55B6.2 P W All gene names: dnj-7; C55B6.2; CE09008; NM_076808;
WBGene00001025; WP:CE09008; XH815
WormBase description: This gene encodes a protein
containing a DnaJ ('J') domain that is predicted to be
mitochondrial.
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster order, Reinke et al 2004, list of genes in
cluster C, ViswanathanM et al 2005 S2 daf-16
Resveratrol, ViswanathanM et al 2005 S2 sir-2.1
regulated, Wang et al 2003 S3 genes pass one-way
ANOVA, Wang et al 2003 S4 Early genes, Wang et al 2003
S4 genes pass two-wayANOVA P0
C55B7.3 Aff_C55B7.3 P W All gene names: C55B7.3; 1H77; CE09014; WBGene00016942;
WP:CE09014
WormBase description: protein-tyrosine phosphatase
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, spermatogenesis
enriched genes, Reinke et al 2004, wt herm vs wt herm
enriched gen, Reinke et al 2004, fem3 enriched genes,
Reinke et al 2004, wt vs glp-4 enriched genes, Reinke
et al 2004, wt males vs glp4 male enriched , Reinke et
al 2004, list of genes in cluster D, Reinke et al 2004,
shared sperm
C55B7.4 Aff_C55B7.4 P W All gene names: acdh-1; dod-12; C55B7.4; C55B7.4b.1;
C55B7.4b.2; C55B7.4b.3; C55B7.4b.4; 1H75; CE09015;
CE32840; NM_059470; NM_181994; WBGene00016943;
WP:CE09015; WP:CE32840
WormBase description: acyl-CoA dehydrogenase
Member of lists (Publications lists):
Bishop et al 2004 T1 Upregulated in
vhl-1 vs WT, Golden et al 2004, N2 differentially
expressed gen, Golden et al 2004, N2 vs daf-2 different
genes at , McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Reinke et al 2004, herm soma enriched genes,
ViswanathanM et al 2005 S2 sir-2.1 regulated
D1005.2 Aff_D1005.2 P W All gene names: D1005.2; CE29741; WBGene00016996;
WP:CE29741; XC81
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster B, ViswanathanM et al 2005 S2 daf-16
Resveratrol, Wang et al 2003 S3 genes pass one-way
ANOVA, Wang et al 2003 S4 LateList, Wang et al 2003
S4 genes pass two-wayANOVA P0
D1025.2 Aff_D1025.2 P W All gene names: D1025.2; CE17610; WBGene00008354;
WP:CE17610; XP132
WormBase description: This gene encodes a protein
predicted by Eisenberg and coworkers, with 52%
accuracy, to be mitochondrial.
Member of lists (Publications lists):
McCarroll et al 2004 SFig5 conserved
w/ yeast, McCarroll et al 2004 SFig1-4 conserved w/
Drosoph, Wang et al 2003 S4 Early genes, Wang et al
2003 S3 genes pass one-way ANOVA, Wang et al 2003 S4
genes pass two-wayANOVA P0
D1044.6 Aff_D1044.6 P W All gene names: D1044.6; 3G626; CE32173;
WBGene00017031; WP:CE32173
Member of lists (Publications lists):
Jones et al 2001 Non dauer genes
P<0.05, Reinke et al 2004, list of genes in cluster F,
Reinke et al 2004, fem1 enriched genes, Reinke et al
2004, wt vs glp-4 enriched genes, Reinke et al 2004,
list of genes in cluster order, Reinke et al 2004,
oogenesis enriched genes, Reinke et al 2004, wt herm vs
wt male enriched gen
D1053.1 Aff_D1053.1 P W All gene names: gst-42; D1053.1; CE03099; NM_077561;
WBGene00001790; WP:CE03099; XM346
WormBase description: gst-42 is orthologous to the
human gene GLUTATHIONE TRANSFERASE ZETA-1 (also known
as MALEYLACETOACETATE ISOMERASE; GSTZ1; OMIM:603758),
which when mutated is thought to lead to a variety of
type I tyrosinemia.
WormBase CDS description: glutathione S-transferase
Member of lists (Publications lists):
Kwon et al 2004 T1 late-repression
Ethanol-respon, McCarroll et al 2004 SFig1-4 conserved
w/ Drosoph, Reinke et al 2004, list of genes in cluster
order, Reinke et al 2004, list of genes in cluster C,
Romagnolo et al 2002 Fig3b Oxidation, ViswanathanM et
al 2005 S2 sir-2.1 regulated, Wang et al 2003 S4
Climbing, Wang et al 2003 S3 genes pass one-way
ANOVA, Wang et al 2003 S4 genes pass two-wayANOVA P0
D1081.2 Aff_D1081.2 P W All gene names: unc-120; D1081.2; 1J37; CE05534;
NM_059895; WBGene00006844; WP:CE05534
WormBase description: unc-120 encodes a member of the
MADS-box family of transcription factors that contains
human and Drosophila serum response factor (SRF) and
Saccharomyces cerevisiae MCM1 and ARG80; UNC-120 is
required for locomotion and muscle development and for
formation of the normal number of muscle A and I bands;
UNC-120 is also required for maintaining wild-type
expression levels of the muscle components actin and
myosin; UNC-120 is first expressed in the early embryo
in body wall muscle precursors and later is expressed
in both body wall and vulval muscles.
WormBase CDS description: MADS domain
Member of lists (Publications lists):
Baugh et al 2005, validated PAL-1
target genes, Baugh et al 2005, PAL-1 target genes,
McCarroll et al 2004 SFig5 conserved w/ yeast,
McCarroll et al 2004 SFig1-4 conserved w/ Drosoph,
Reinke et al 2004, list of genes in cluster A, Reinke
et al 2004, list of genes in cluster order
D2045.7 Aff_D2045.7 P W All gene names: D2045.7; 3L565; CE37761;
WBGene00008424; WP:CE37761
WormBase description: serine/threonine kinase
Member of lists (Publications lists):
Jones et al 2001 Dauer specific genes
P<0.05, McCarroll et al 2004 SFig5 conserved w/ yeast,
Reinke et al 2004, mixed sperm soma, Reinke et al 2004,
GO categories, Reinke et al 2004, fem3 enriched genes,
Wang et al 2003 S7 SAGE genes in the dataset, Wang et
al 2003 S8 SAGE genes in the dauer exit
D2045.9 Aff_D2045.9 P W All gene names: D2045.9; CE33988; WBGene00008426;
WP:CE33988
Member of lists (Publications lists):
Romagnolo et al 2002 Fig3b Unkown,
ViswanathanM et al 2005 S2 sir-2.1 regulated, Wang et
al 2003 S4 Early genes, Wang et al 2003 S3 genes
pass one-way ANOVA, Wang et al 2003 S4 genes pass
two-wayANOVA P0
D2096.1 Aff_D2096.1 P W All gene names: D2096.1; 4J163; CE04299;
WBGene00017069; WP:CE04299
Member of lists (Publications lists):
Reinke et al 2004, intrinsic, Reinke
et al 2004, wt vs glp-4 enriched genes, Reinke et al
2004, GO categories, ViswanathanM et al 2005 S2
sir-2.1 regulated, Wang et al 2003 S5 genes common to
feeding ANOVA, Wang et al 2003 S3 genes pass one-way
ANOVA
DY3.3 Aff_DY3.3 P W All gene names: hlh-16; DY3.3; 1J342; CE15747;
NM_059971; WBGene00001960; WP:CE15747
WormBase description: Helix-loop-helix DNA-binding
domain
E03E2.1 Aff_E03E2.1 P W All gene names: cyp-43A1; E03E2.1; E03E2.1.1;
E03E2.1.2; CE29747; NM_076560; WBGene00017108;
WP:CE29747; XG335
WormBase description: cytochrome P450
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
E04A4.1 Aff_E04A4.1 P W All gene names: fbxb-78; E04A4.1; 4F501; CE32346;
WBGene00017116; WP:CE32346
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; its encoded
protein also contains a Pfam-B45 motif of presently
unknown function.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
E04F6.2 Aff_E04F6.2 P W All gene names: E04F6.2; 2H491; CE01214;
WBGene00017122; WP:CE01214
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, ViswanathanM et al 2005 S2
sir-2.1 regulated
E04F6.3 Aff_E04F6.3 P W All gene names: maoc-1; E04F6.3; 2H487; CE01215;
WBGene00017123; WP:CE01215
WormBase description: E04F6.3 encodes a protein that is
orthologous (with 52% identity over 93% of its length)
to residues 334-609 of human 17-BETA-HYDROXYSTEROID
DEHYDROGENASE IV (HSD17B4; OMIM:601860, mutated in
D-bifunctional protein deficiency), a protein of 736
residues whose N- and C-terminal domains are
orthologous to DHS-28; E04F6.3 contains a MaoC-like
domain, found in diverse enzymes (HSD17B4, peroxisomal
hydratase-dehydrogenase-epimerase, and the fatty acid
synthase beta subunit); E04F6.3 has no obvious function
in mass RNAi assays.
WormBase CDS description:
Hydratase-dehydrogenase-epimerase
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster C, ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol, Wang et al 2003 S6 removed genes of
contamination
EEED8.12 Aff_EEED8.12 P W All gene names: EEED8.12; 2F700; CE01885;
WBGene00017140; WP:CE01885
WormBase description: Probable RNA binding protein
Member of lists (Publications lists):
Reinke et al 2004, GO categories,
Reinke et al 2004, IVb male soma enriched genes,
ViswanathanM et al 2005 S2 sir-2.1 regulated
F01G10.2 Aff_F01G10.2 P W All gene names: ech-8; F01G10.2; 4L2; CE35450;
NM_069475; WBGene00001157; WP:CE35450
WormBase description: enoyl-CoA hydratase
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster B, ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol
F01G10.7 Aff_F01G10.7 P W All gene names: F01G10.7; 4L4; CE09169; WBGene00008510;
WP:CE09169
WormBase description: triacylglycerol lipase
Member of lists (Publications lists):
Jones et al 2001 Non dauer genes
P<0.05
F07A5.7 Aff_F07A5.7 P W All gene names: unc-15; F07A5.7; F07A5.7.1; F07A5.7.2;
F07A5.7.3; F07A5.7.4; 1H954; CE09197; NM_059684;
WBGene00006754; WP:CE09197
WormBase description: The unc-15 gene encodes a
paramyosin ortholog; UNC-15 protein physically
interacts with MHC A, one isoform of myosin heavy chain
(MHC) in striated muscle; UNC-15 accumulation is
decreased in the absence of UNC-54 (myosin B), implying
that degradation of UNC-15 is inhibited by its binding
myosin B; conversely, myosin B (but not MYO-3/myosin A)
fails to accumulate in unc-15 mutants.
WormBase CDS description: paramyosin
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster order, Reinke et al 2004, list of genes in
cluster C, Reinke et al 2004, IVb male soma enriched
genes, Roy et al 2002 S2 positivecontrol L1 muscle,
ViswanathanM et al 2005 S2 sir-2.1 regulated
F07E5.2 Aff_F07E5.2 P W All gene names: fbxb-35; F07E5.2; 2C343; CE09215;
WBGene00017208; WP:CE09215
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; its encoded
protein also contains a Pfam-B45 motif of presently
unknown function.
Member of lists (Publications lists):
ViswanathanM et al 2005 S2 sir-2.1
regulated
F07E5.6 Aff_F07E5.6 P W All gene names: fbxb-36; F07E5.6; 2C348; CE09218;
WBGene00017211; WP:CE09218
Member of lists (Publications lists):
Reinke et al 2004, mixed sperm soma,
Reinke et al 2004, fem3 enriched genes
F08A8.1 Aff_F08A8.1 P W All gene names: F08A8.1; F08A8.1a.1; F08A8.1a.2;
F08A8.1b.1; F08A8.1b.2; F08A8.1b.3; F08A8.1b.4;
F08A8.1c.1; F08A8.1c.2; 1N533; CE17633; CE36125;
CE39570; WBGene00008564; WP:CE17633; WP:CE36125;
WP:CE39570
WormBase description: F08A8.1 is orthologous to the
human gene ACYL-CoA OXIDASE 1, PALMITOYL (ACOX1;
OMIM:264470), which when mutated leads to
pseudoneonatal adrenoleukodystrophy.
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster C, Reinke et al 2004, GO categories, Reinke et
al 2004, herm soma enriched genes, ViswanathanM et al
2005 S2 sir-2.1 regulated
F08B12.2 Aff_F08B12.2 P W All gene names: prx-12; F08B12.2; CE03163; NM_077507;
WBGene00004197; WP:CE03163; XM13
WormBase description: Zinc finger, C3HC4 type (RING
finger)
Member of lists (Publications lists):
McCarroll et al 2004 SFig1-4
conserved w/ Drosoph, Reinke et al 2004, list of genes
in cluster order, Reinke et al 2004, list of genes in
cluster B, ViswanathanM et al 2005 S2 sir-2.1
regulated, ViswanathanM et al 2005 S2 daf-16
Resveratrol, Wang et al 2003 S4 TransientList, Wang et
al 2003 S3 genes pass one-way ANOVA, Wang et al 2003
S4 genes pass two-wayANOVA P0
F08D12.10 Aff_F08D12.10 P W All gene names: fbxb-110; sdz-9; F08D12.10; 2D62;
CE09243; WBGene00017253; WP:CE09243
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; its encoded
protein also contains a Pfam-B45 motif of presently
unknown function.
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, Reinke et al 2004, list of genes in
cluster E
F08D12.11 Aff_F08D12.11 P W All gene names: fbxb-111; F08D12.11; 2D64; CE09244;
WBGene00017254; WP:CE09244
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; its encoded
protein also contains a Pfam-B45 motif of presently
unknown function.
F08D12.8 Aff_F08D12.8 P W All gene names: fbxb-105; F08D12.8; 2D58; CE09241;
WBGene00017251; WP:CE09241
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; its encoded
protein also contains a Pfam-B45 motif of presently
unknown function.
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, ViswanathanM et al 2005 S2 daf-16
Resveratrol
F08D12.9 Aff_F08D12.9 P W All gene names: fbxb-109; sdz-10; F08D12.9; 2D60;
CE09242; WBGene00017252; WP:CE09242
WormBase description: This gene encodes a protein
containing an F-box, a motif predicted to mediate
protein-protein interactions either with homologs of
yeast Skp-1p or with other proteins; its encoded
protein also contains a Pfam-B45 motif of presently
unknown function.
Member of lists (Publications lists):
Reinke et al 2004, list of genes in
cluster order, ViswanathanM et al 2005 S2 daf-16
Resveratrol
F08G12.1 Aff_F08G12.1 P W All gene names: F08G12.1; CE03166; WBGene00008585;
WP:CE03166; XL922
WormBase description: ras-related like protein
F08G2.7 Aff_F08G2.7 P W All gene names: F08G2.7; 2O128; CE19779;
WBGene00008578; WP:CE19779
F08H9.3 Aff_F08H9.3 P W All gene names: F08H9.3; 5O942; CE09267;
WBGene00008591; WP:CE09267
WormBase description: F08H9.3 encodes a heat shock
protein (HSP) of the HSP16 class; unlike most HSP16s in
C. elegans, it is specifically expressed in a
particular tissue (the larval pharynx and the anterior
adult pharynx), and its expression is not strongly
induced by heat shock; however, F08H9.3 expression is
increased by heat shock (with adult expression in the
full pharynx) and probably aids heat shock resistance,
since F08H9.3(RNAi) animals have sensitivity to heat
shock that is sporadically higher than normal; in
general, HSP16 proteins are thought to act as passive
ligands for unfolded proteins that keep them safe from
aggregation until the proteins can be refolded by a
large (ATP-consuming) HSP.
